Mechanism of epithelial‐mesenchymal transition in cancer and its regulation by natural compounds

HL Ang, CD Mohan, MK Shanmugam… - Medicinal research …, 2023 - Wiley Online Library
Epithelial‐mesenchymal transition (EMT) is a complex process with a primordial role in
cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal …

[HTML][HTML] Colon cancer and colorectal cancer: Prevention and treatment by potential natural products

MR Islam, S Akash, MM Rahman, FT Nowrin… - Chemico-biological …, 2022 - Elsevier
Colon cancer affects both men and women and is the world's second most significant cause
of cancer-related mortality. Colon cancer death rates have risen worldwide due to the …

[HTML][HTML] The therapeutic potential of apigenin

B Salehi, A Venditti, M Sharifi-Rad, D Kręgiel… - International journal of …, 2019 - mdpi.com
Several plant bioactive compounds have exhibited functional activities that suggest they
could play a remarkable role in preventing a wide range of chronic diseases. The largest …

[HTML][HTML] Phytochemicals in cancer treatment: From preclinical studies to clinical practice

AS Choudhari, PC Mandave, M Deshpande… - Frontiers in …, 2020 - frontiersin.org
Cancer is a severe health problem that continues to be a leading cause of death worldwide.
Increasing knowledge of the molecular mechanisms underlying cancer progression has led …

Selective cytotoxicity of green synthesized silver nanoparticles against the MCF-7 tumor cell line and their enhanced antioxidant and antimicrobial properties

S Khorrami, A Zarrabi, M Khaleghi… - International journal …, 2018 - Taylor & Francis
Introduction Silver nanoparticles (AgNPs) are of great interest due to their unique and
controllable characteristics. Different synthesis methods have been proposed to produce …

A review on flavonoid apigenin: Dietary intake, ADME, antimicrobial effects, and interactions with human gut microbiota

M Wang, J Firrman, LS Liu… - BioMed research …, 2019 - Wiley Online Library
Apigenin is a flavonoid of low toxicity and multiple beneficial bioactivities. Published reviews
all focused on the findings using eukaryotic cells, animal models, or epidemiological studies …

Functionality of apigenin as a potent antioxidant with emphasis on bioavailability, metabolism, action mechanism and in vitro and in vivo studies: A review

P Kashyap, D Shikha, M Thakur… - Journal of food …, 2022 - Wiley Online Library
Numerous diseases such as cancer, diabetes, cardiovascular, neurodegenerative diseases,
etc. are linked with overproduction of reactive oxygen species (ROS) and oxidative stress …

Enhancement of bioavailability and bioactivity of diet-derived flavonoids by application of nanotechnology: A review

H Teng, Y Zheng, H Cao, Q Huang… - Critical Reviews in …, 2023 - Taylor & Francis
Flavonoids, which are a class of polyphenols widely existing in food and medicine, have
enormous pharmacological effects. The functional properties of flavonoids are mainly …

[HTML][HTML] Apigenin ameliorates doxorubicin-induced renal injury via inhibition of oxidative stress and inflammation

Q Wu, W Li, J Zhao, W Sun, Q Yang, C Chen… - Biomedicine & …, 2021 - Elsevier
Background and objective Doxorubicin (DOX) is an anthracycline antitumor antibiotic widely
utilized in treating various tumors. Nevertheless, the toxicity of DOX toward normal cells …

[HTML][HTML] Effects of apigenin on RBL-2H3, RAW264. 7, and HaCaT cells: anti-allergic, anti-inflammatory, and skin-protective activities

CH Park, SY Min, HW Yu, K Kim, S Kim, HJ Lee… - International Journal of …, 2020 - mdpi.com
Apigenin (4′, 5, 7-trihydroxyflavone, flavonoid) is a phenolic compound that is known to
reduce the risk of chronic disease owing to its low toxicity. The first study on apigenin …