[HTML][HTML] Type II diabetes mellitus: a review on recent drug based therapeutics

S Padhi, AK Nayak, A Behera - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Diabetes mellitus (DM) is a metabolic disorder that occurs in the body because of decreased
insulin activity and/or insulin secretion. Pathological changes such as nephropathy …

[HTML][HTML] Type 2 diabetes mellitus: a review of multi-target drugs

A Artasensi, A Pedretti, G Vistoli, L Fumagalli - Molecules, 2020 - mdpi.com
Diabetes Mellitus (DM) is a multi-factorial chronic health condition that affects a large part of
population and according to the World Health Organization (WHO) the number of adults …

Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums

SE Arnold, Z Arvanitakis… - Nature Reviews …, 2018 - nature.com
Considerable overlap has been identified in the risk factors, comorbidities and putative
pathophysiological mechanisms of Alzheimer disease and related dementias (ADRDs) and …

[HTML][HTML] Excess body weight: Novel insights into its roles in obesity comorbidities

X Zhang, S Ha, HCH Lau, J Yu - Seminars in Cancer Biology, 2023 - Elsevier
Excess body weight is a global health problem due to sedentary lifestyle and unhealthy diet,
affecting 2 billion population worldwide. Obesity is a major risk factor for metabolic diseases …

[HTML][HTML] Genetics of type 2 diabetes—pitfalls and possibilities

RB Prasad, L Groop - Genes, 2015 - mdpi.com
Type 2 diabetes (T2D) is a complex disease that is caused by a complex interplay between
genetic, epigenetic and environmental factors. While the major environmental factors, diet …

Co‐shared genetics and possible risk gene pathway partially explain the comorbidity of schizophrenia, major depressive disorder, type 2 diabetes, and metabolic …

TT Postolache, L del Bosque‐Plata… - American Journal of …, 2019 - Wiley Online Library
Schizophrenia (SCZ) and major depressive disorder (MDD) in treatment‐naive patients are
associated with increased risk for type 2 diabetes (T2D) and metabolic syndrome (MetS) …

Genetic predisposition in type 2 diabetes: a promising approach toward a personalized management of diabetes

MM Sirdah, NS Reading - Clinical Genetics, 2020 - Wiley Online Library
Diabetes mellitus, also known simply as diabetes, has been described as a chronic and
complex endocrine metabolic disorder that is a leading cause of death across the globe. It is …

Evaluation of synthetic 2-aryl quinoxaline derivatives as α-amylase, α-glucosidase, acetylcholinesterase, and butyrylcholinesterase inhibitors

S Hameed, KM Khan, P Taslimi, U Salar… - International Journal of …, 2022 - Elsevier
Variety of 2-aryl quinoxaline derivatives 1–23 were synthesized in good yields, by reacting
1, 2-phenylenediamine with varyingly substituted phenacyl bromides in the presence of …

[HTML][HTML] Type 3 diabetes: Cross talk between differentially regulated proteins of type 2 diabetes mellitus and Alzheimer's disease

K Mittal, RJ Mani, DP Katare - Scientific reports, 2016 - nature.com
Abstract Type 3 Diabetes (T3D) is a neuroendocrine disorder that represents the
progression of Type 2 Diabetes Mellitus (T2DM) to Alzheimer's disease (AD). T3D …

[HTML][HTML] Comprehensive approach to medical nutrition therapy in patients with type 2 diabetes mellitus: from diet to bioactive compounds

L Barrea, C Vetrani, L Verde, E Frias-Toral, F Ceriani… - Antioxidants, 2023 - mdpi.com
In the pathogenesis of type 2 diabetes mellitus (T2DM), diet plays a key role. Individualized
medical nutritional therapy, as part of lifestyle optimization, is one of the cornerstones for the …