Background Misconceptions and errors in the management of periprosthetic joint infection
(PJI) can compromise the treatment success. The goal of this paper is to systematically …

Bone is a complex tissue with a variety of functions, such as providing mechanical stability
for locomotion, protection of the inner organs, mineral homeostasis and haematopoiesis. To …

Metallic implants are frequently used in medicine to support and replace degenerated
tissues. Implant loosening due to particle exposure remains a major cause for revision …

A bacterial infection on the surface of medical apparatus and instruments as well as artificial
implants is threatening human health greatly. Antibiotics and traditional bacterial-killing …

Heterogeneous populations of human bone marrow-derived stromal cells (BMSC) are
among the most frequently tested cellular therapeutics for treating degenerative and immune …

Off-the-shelf hip joints are considered essential parts in rehabilitation medicine that can help
the disabled. However, the failure of the materials used in such joints can cause individual …

Over the last decades, joint arthroplasty has become a successful treatment for joint disease.
Nowadays, with a growing demand and increasingly younger and active patients accepting …

Replacing the diseased joints with artificial prostheses has long been a common medical
mean to alleviate pain or disability, in which the wear debris-induced aseptic loosening is …

Osteoarthritis disorder ranks amongst the most common disabling chronic diseases in young
and older adults worldwide. It is linked to degenerative joint diseases and frequently occurs …

Increased failure rates due to metallic wear particle-associated adverse local tissue
reactions (ALTR) is a significant clinical problem in resurfacing and total hip arthroplasty …