Homocysteine and its derivatives as possible modulators of neuronal and non-neuronal cell glutamate receptors in Alzheimer's disease

AA Boldyrev, P Johnson - Journal of Alzheimer's Disease, 2007 - content.iospress.com
Homocysteine (HC) and its derivatives may be involved in the etiology of Alzheimer's
Disease (AD), although the precise mechanisms by which these compounds could cause …

New insights into the neurodegeneration mechanisms underlying riboflavin transporter deficiency (RTD): involvement of energy dysmetabolism and cytoskeletal …

F Colasuonno, C Marioli, M Tartaglia, E Bertini… - Biomedicines, 2022 - mdpi.com
Riboflavin transporter deficiency (RTD) is a rare genetic disorder characterized by motor,
sensory and cranial neuropathy. This childhood-onset neurodegenerative disease is caused …

Neuroprotective effect of honokiol and magnolol, compounds from Magnolia officinalis, on beta‐amyloid‐induced toxicity in PC12 cells

CP Hoi, YP Ho, L Baum, AHL Chow - Phytotherapy Research, 2010 - Wiley Online Library
Amyloid β peptide (Aβ) induced toxicity is a well‐established pathway of neuronal cell death
which might play a role in Alzheimer's disease. In this regard, the toxic effect of Aβ on a …

Protection of neuronal cells against reactive oxygen species by carnosine and related compounds

A Boldyrev, E Bulygina, T Leinsoo… - … and Physiology Part B …, 2004 - Elsevier
Carnosine and related compounds were compared in terms of their abilities to decrease the
levels of reactive oxygen species (ROS) in suspensions of isolated neurons activated by N …

[HTML][HTML] Ouabain activates signaling pathways associated with cell death in human neuroblastoma

A Kulikov, A Eva, U Kirch, A Boldyrev… - … et Biophysica Acta (BBA …, 2007 - Elsevier
Cardiotonic steroids (CTS) like ouabain are not only specific inhibitors of the sodium pump
(Na+, K+-ATPase), they also can influence various cytosolic signaling events in a hormone …

Роль активных форм кислорода в жизнедеятельности нейрона

АА Болдырев - Успехи физиологических наук, 2003 - elibrary.ru
В обзоре рассмотрено участие активных форм кислорода (АФК) в метаболизме
нейрональных клеток, их повреждающее действие на белки, липиды и нуклеиновые …

Rodent lymphocytes express functionally active glutamate receptors

AA Boldyrev, VI Kazey, TA Leinsoo… - Biochemical and …, 2004 - Elsevier
RT-PCR demonstrated that ionotropic (iGluR NR1) and metabotropic (mGluR Group III)
glutamate receptors are expressed in rodent lymphocytes. Flow cytometry showed that …

Na-K-ATPase in rat cerebellar granule cells is redox sensitive

I Petrushanko, N Bogdanov… - American Journal …, 2006 - journals.physiology.org
Redox-induced regulation of the Na-K-ATPase was studied in dispersed rat cerebellar
granule cells. Intracellular thiol redox state was modulated using glutathione (GSH) …

The excitotoxic effect of NMDA on human lymphocyte immune function

AP Mashkina, OV Tyulina, TI Solovyova… - Neurochemistry …, 2007 - Elsevier
N-Methyl-d-aspartate (NMDA)-activated glutamate receptors are expressed in lymphocytes,
but their roles have not yet been defined. We show that incubation of human peripheral …

Biological activity of novel synthetic derivatives of carnosine

SL Stvolinsky, ER Bulygina, TN Fedorova… - Cellular and molecular …, 2010 - Springer
Two novel derivatives of carnosine—(S)-trolox-l-carnosine (STC) and (R)-trolox-l-carnosine
(RTC) are characterized in terms of their antioxidant and membrane-stabilizing activities as …