Priority effects in microbiome assembly

R Debray, RA Herbert, AL Jaffe… - Nature Reviews …, 2022 - nature.com
Advances in next-generation sequencing have enabled the widespread measurement of
microbiome composition across systems and over the course of microbiome assembly …

Blautia—a new functional genus with potential probiotic properties?

X Liu, B Mao, J Gu, J Wu, S Cui, G Wang, J Zhao… - Gut …, 2021 - Taylor & Francis
Blautia is a genus of anaerobic bacteria with probiotic characteristics that occur widely in the
feces and intestines of mammals. Based on phenotypic and phylogenetic analyses, some …

[HTML][HTML] Producing polished prokaryotic pangenomes with the Panaroo pipeline

G Tonkin-Hill, N MacAlasdair, C Ruis, A Weimann… - Genome biology, 2020 - Springer
Population-level comparisons of prokaryotic genomes must take into account the substantial
differences in gene content resulting from horizontal gene transfer, gene duplication and …

Species-level functional profiling of metagenomes and metatranscriptomes

EA Franzosa, LJ McIver, G Rahnavard, LR Thompson… - Nature …, 2018 - nature.com
Functional profiles of microbial communities are typically generated using comprehensive
metagenomic or metatranscriptomic sequence read searches, which are time-consuming …

Structure and function of the global topsoil microbiome

M Bahram, F Hildebrand, SK Forslund, JL Anderson… - Nature, 2018 - nature.com
Soils harbour some of the most diverse microbiomes on Earth and are essential for both
nutrient cycling and carbon storage. To understand soil functioning, it is necessary to model …

[HTML][HTML] Open-access bacterial population genomics: BIGSdb software, the PubMLST. org website and their applications

KA Jolley, JE Bray, MCJ Maiden - Wellcome open research, 2018 - ncbi.nlm.nih.gov
The PubMLST. org website hosts a collection of open-access, curated databases that
integrate population sequence data with provenance and phenotype information for over …

[HTML][HTML] 1,520 reference genomes from cultivated human gut bacteria enable functional microbiome analyses

Y Zou, W Xue, G Luo, Z Deng, P Qin, R Guo… - Nature …, 2019 - nature.com
Reference genomes are essential for metagenomic analyses and functional characterization
of the human gut microbiota. We present the Culturable Genome Reference (CGR), a …

UniProt: the universal protein knowledgebase

Nucleic acids research, 2017 - academic.oup.com
The UniProt knowledgebase is a large resource of protein sequences and associated
detailed annotation. The database contains over 60 million sequences, of which over half a …

Pan-genomics in the human genome era

RM Sherman, SL Salzberg - Nature Reviews Genetics, 2020 - nature.com
Since the early days of the genome era, the scientific community has relied on a single
'reference'genome for each species, which is used as the basis for a wide range of genetic …

Roary: rapid large-scale prokaryote pan genome analysis

AJ Page, CA Cummins, M Hunt, VK Wong… - …, 2015 - academic.oup.com
A typical prokaryote population sequencing study can now consist of hundreds or thousands
of isolates. Interrogating these datasets can provide detailed insights into the genetic …