Molecular mechanisms that mediate dendrite morphogenesis

JL Lefebvre - Current topics in developmental biology, 2021 - Elsevier
Neurons develop dendritic morphologies that bear cell type-specific features in dendritic
field size and geometry, branch placement and density, and the types and distributions of …

Activity regulates brain development in the fly

O Akin, SL Zipursky - Current opinion in genetics & development, 2020 - Elsevier
It has long been appreciated that activity sculpts the formation of neuronal circuits in the
mammalian brain. By contrast, in Drosophila it was generally thought that genetically …

Structural and developmental principles of neuropil assembly in C. elegans

MW Moyle, KM Barnes, M Kuchroo, A Gonopolskiy… - Nature, 2021 - nature.com
Neuropil is a fundamental form of tissue organization within the brain, in which densely
packed neurons synaptically interconnect into precise circuit architecture,. However, the …

Modular transcriptional programs separately define axon and dendrite connectivity

YZ Kurmangaliyev, J Yoo, SA LoCascio, SL Zipursky - Elife, 2019 - elifesciences.org
Patterns of synaptic connectivity are remarkably precise and complex. Single-cell RNA
sequencing has revealed a vast transcriptional diversity of neurons. Nevertheless, a clear …

Interactions between Dpr11 and DIP-γ control selection of amacrine neurons in Drosophila color vision circuits

KP Menon, V Kulkarni, S Takemura, M Anaya, K Zinn - Elife, 2019 - elifesciences.org
Drosophila R7 UV photoreceptors (PRs) are divided into yellow (y) and pale (p) subtypes.
yR7 PRs express the Dpr11 cell surface protein and are presynaptic to Dm8 amacrine …

Modality-specific circuits for skylight orientation in the fly visual system

G Sancer, E Kind, H Plazaola-Sasieta, J Balke, T Pham… - Current Biology, 2019 - cell.com
In the fly optic lobe,∼ 800 highly stereotypical columnar microcircuits are arranged
retinotopically to process visual information. Differences in cellular composition and synaptic …

Better Sleep at Night: How Light Influences Sleep in Drosophila

GM Mazzotta, M Damulewicz, P Cusumano - Frontiers in Physiology, 2020 - frontiersin.org
Sleep-like states have been described in Drosophila and the mechanisms and factors that
generate and define sleep-wake profiles in this model organism are being thoroughly …

Differential adhesion regulates neurite placement via a retrograde zippering mechanism

T Sengupta, NL Koonce, N Vázquez-Martínez… - Elife, 2021 - elifesciences.org
During development, neurites and synapses segregate into specific neighborhoods or
layers within nerve bundles. The developmental programs guiding placement of neurites in …

A Closer Look at Histamine in Drosophila

C Volonté, F Liguori, S Amadio - International Journal of Molecular …, 2024 - mdpi.com
The present work intends to provide a closer look at histamine in Drosophila. This choice is
motivated firstly because Drosophila has proven over the years to be a very simple, but …

Development of the Drosophila optic lobe

Y Zhang, X Li - Cold Spring Harbor Protocols, 2024 - cshprotocols.cshlp.org
The Drosophila visual system has been a great model to study fundamental questions in
neurobiology, such as neural fate specification, axon guidance, circuit formation, and …