Glioblastoma (GBM) is a devastating type of brain tumor, and current therapeutic treatments,
including surgery, chemotherapy, and radiation, are palliative at best. The design of effective …

Glioblastoma multiforme (GBM) is the most aggressive and common malignant primary brain
tumor. Patients with GBM often have poor prognoses, with a median survival of∼ 15 months …

Glioma is often referred to as one of the most dreadful central nervous system (CNS)-specific
tumors with rapidly-proliferating cancerous glial cells, accounting for nearly half of the brain …

Comparative oncology is a field of study that has been recently adopted for studying cancer
and developing cancer therapies. Companion animals such as dogs can be used to …

Simple Summary Despite the continuous development of treatment technology,
glioblastoma remains a challenge for modern medicine. The standard of care remains a …

Malignant brain tumors, known as H3K27-altered diffuse midline glioma (DMG) and H3G34-
mutant diffuse hemispheric glioma (DHG), can affect individuals of all ages and are …

Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer.
Although great efforts have been made by clinicians and researchers, no significant …

Background: Glioma is the most prevalent central nervous system tumor in humans, and its
prognosis remains unsatisfactory due to a lack of effective therapeutic targets. The ectopic …

Glioblastoma multiforme is one of the calamitous primary glial brain tumors with extensive
heterogeneity at cellular and molecular levels. While maximal surgical resection trailed by …

Background Metabolism reprogramming plays a vital role in glioblastoma (GBM)
progression and recurrence by producing enough energy for highly proliferating tumor cells …