Glucocorticoid signaling: an update from a genomic perspective

MA Sacta, Y Chinenov, I Rogatsky - Annual review of physiology, 2016 - annualreviews.org
Glucocorticoid hormones (GC) regulate essential physiological functions including energy
homeostasis, embryonic and postembryonic development, and the stress response. From …

Circadian metabolism: from mechanisms to metabolomics and medicine

SA Brown - Trends in Endocrinology & Metabolism, 2016 - cell.com
The circadian clock directs nearly all aspects of diurnal physiology, including metabolism.
Current research identifies several major axes by which it exerts these effects, including …

Multilevel interactions of stress and circadian system: implications for traumatic stress

A Agorastos, NC Nicolaides, VP Bozikas… - Frontiers in …, 2020 - frontiersin.org
The dramatic fluctuations in energy demands by the rhythmic succession of night and day on
our planet has prompted a geophysical evolutionary need for biological temporal …

Forced rather than voluntary exercise entrains peripheral clocks via a corticosterone/noradrenaline increase in PER2:: LUC mice

H Sasaki, Y Hattori, Y Ikeda, M Kamagata, S Iwami… - Scientific reports, 2016 - nature.com
Exercise during the inactive period can entrain locomotor activity and peripheral circadian
clock rhythm in mice; however, mechanisms underlying this entrainment are yet to be …

Functional zonation of the adult mammalian adrenal cortex

GP Vinson - Frontiers in Neuroscience, 2016 - frontiersin.org
The standard model of adrenocortical zonation holds that the three main zones,
glomerulosa, fasciculata, and reticularis each have a distinct function, producing …

Circadian and photic modulation of daily rhythms in diurnal mammals

L Yan, L Smale, AA Nunez - European Journal of Neuroscience, 2020 - Wiley Online Library
The temporal niche that an animal occupies includes a coordinated suite of behavioral and
physiological processes that set diurnal and nocturnal animals apart. The daily rhythms of …

The interplay between stress, circadian clocks, and energy metabolism

H Oster - Journal of Endocrinology, 2020 - joe.bioscientifica.com
Endogenous circadian clocks adapt an organism's physiology and behavior to predictable
changes in the environment as a consequence of the Earth's rotation around its axis. In …

The circadian clock in the regulation of renal rhythms

K Solocinski, ML Gumz - Journal of biological rhythms, 2015 - journals.sagepub.com
Since the kidney is integral to maintenance of fluid and ion homeostasis, and therefore
blood pressure regulation, its proper function is paramount. Circadian fluctuations in blood …

Fixing the broken clock in adrenal disorders: focus on glucocorticoids and chronotherapy

M Minnetti, V Hasenmajer, R Pofi… - Journal of …, 2020 - joe.bioscientifica.com
The circadian rhythm derives from the integration of many signals that shape the expression
of clock-related genes in a 24-hour cycle. Biological tasks, including cell proliferation …

Coupling the circadian clock to homeostasis: the role of period in timing physiology

P Kim, H Oster, H Lehnert, SM Schmid… - Endocrine …, 2019 - academic.oup.com
A plethora of physiological processes show stable and synchronized daily oscillations that
are either driven or modulated by biological clocks. A circadian pacemaker located in the …