Hydrophilic interaction liquid chromatography promotes the development of bio-separation and bio-analytical chemistry

Q Sheng, M Liu, M Lan, G Qing - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Hydrophilic interaction liquid chromatography (HILIC) has inherent advantages in the
separation of hydrophilic or strongly polar substances (eg, saccharides, glycopeptides …

The metabolomics approaches based on LC-MS/MS for analysis of non-halal meats in food products: A review

A Windarsih, A Rohman, FDO Riswanto, Dachriyanus… - Agriculture, 2022 - mdpi.com
Halal meats are meats that are allowed to be consumed by Muslim societies according to
Islamic law (Syariah). Due to the development of food technology, non-halal meats such as …

Online hydrophilic interaction chromatography (HILIC) enhanced top-down mass spectrometry characterization of the SARS-CoV-2 spike receptor-binding domain

JW Wilson, A Bilbao, J Wang, YC Liao… - Analytical …, 2022 - ACS Publications
SARS-CoV-2 cellular infection is mediated by the heavily glycosylated spike protein.
Recombinant versions of the spike protein and the receptor-binding domain (RBD) are …

Hydrophilic partitioning or surface adsorption? A quantitative assessment of retention mechanisms for hydrophilic interaction chromatography (HILIC)

Y Guo, D Baran - Molecules, 2023 - mdpi.com
Retention mechanisms in HILIC have been investigated and reported in literature. However,
the current understanding of retention mechanisms is qualitative and lacks quantitative …

Development of an approach to determining enzymatic activity of ribonucleoside hydrolase c using hydrophilic interaction liquid chromatography

LA Shaposhnikov, NY Chikurova… - … of Chromatography A, 2024 - Elsevier
Abstract Ribonucleoside hydrolase C (RihC, EC 3.2. 2.1–3.2. 2.3, 3.2. 2.7, 3.2. 2.8) belongs
to the family of ribonucleoside hydrolases that catalyze the cleavage of both purine and …

[HTML][HTML] A comparison of hydrophilic interaction liquid chromatography and capillary electrophoresis for the metabolomics analysis of human serum

L Narduzzi, M del Mar Delgado-Povedano… - … of Chromatography A, 2023 - Elsevier
Cationic, anionic, zwitterionic and, partially polar metabolites are very important constituents
of blood serum. Several of these metabolites underpin the core metabolism of cells (eg …

Augmented region of interest for untargeted metabolomics mass spectrometry (AriumMS) of multi-platform-based CE-MS and LC-MS data

L Naumann, A Haun, A Höchsmann, M Mohr… - Analytical and …, 2023 - Springer
In mass spectrometry (MS)-based metabolomics, there is a great need to combine different
analytical separation techniques to cover metabolites of different polarities and apply …

The role of metabolomics in informing strategies for improving photosynthesis

P Westhoff, APM Weber - Journal of Experimental Botany, 2024 - academic.oup.com
Photosynthesis plays a vital role in acclimating to and mitigating climate change, providing
food and energy security for a population that is constantly growing, and achieving an …

[HTML][HTML] Recent advances and current challenges in hydrophilic interaction chromatography for the analysis of therapeutic oligonucleotides

H Lardeux, V D'Atri, D Guillarme - TrAC Trends in Analytical Chemistry, 2024 - Elsevier
Therapeutic oligonucleotides (ONs) are a new generation of drugs that have captured the
attention of the pharmaceutical industry over the past decade, as evidenced by the FDA …

Use of N‐(4‐aminophenyl)piperidine derivatization to improve organic acid detection with supercritical fluid chromatography‐mass spectrometry

YL Saw, JR Boughton, FL Wroniuk… - Journal of separation …, 2023 - Wiley Online Library
The analysis of organic acids in complex mixtures by LC‐MS can often prove challenging,
especially due to the poor sensitivity of negative ionization mode required for detection of …