[HTML][HTML] Lipid polymer hybrid nanocarriers: Insights into synthesis aspects, characterization, release mechanisms, surface functionalization and potential implications

S Shah, P Famta, RS Raghuvanshi, SB Singh… - Colloid and Interface …, 2022 - Elsevier
Lipid polymer hybrid nanoparticles (LPHN) are novel systems which are potentially
emerging in the era of nano-medicine. They are core-shell nanostructures which comprise of …

Nanomaterial surface modification toolkit: Principles, components, recipes, and applications

SV Kaymaz, HM Nobar, H Sarıgül, C Soylukan… - Advances in Colloid and …, 2023 - Elsevier
Surface-functionalized nanostructures are at the forefront of biotechnology, providing new
opportunities for biosensors, drug delivery, therapy, and bioimaging applications. The …

New drug delivery systems developed for brain targeting

SU Rawal, BM Patel, MM Patel - Drugs, 2022 - Springer
The blood-brain barrier (BBB) and the blood-cerebrospinal fluid barrier (BCSF) are two of
the most complex and sophisticated concierges that defend the central nervous system …

Polysaccharide-based nanoassemblies: From synthesis methodologies and industrial applications to future prospects

R Bushra, M Ahmad, F Seidi, J Song, Y Jin… - Advances in Colloid and …, 2023 - Elsevier
Polysaccharides, due to their remarkable features, have gained significant prominence in
the sustainable production of nanoparticles (NPs). High market demand and minimal …

[HTML][HTML] Lipid–polymer hybrid nanosystems: a rational fusion for advanced therapeutic delivery

S Jain, M Kumar, P Kumar, J Verma… - Journal of Functional …, 2023 - mdpi.com
Lipid nanoparticles (LNPs) are spherical vesicles composed of ionizable lipids that are
neutral at physiological pH. Despite their benefits, unmodified LNP drug delivery systems …

[HTML][HTML] Potential role of nanoparticles in treating the accumulation of amyloid-beta peptide in Alzheimer's patients

M Abbas - Polymers, 2021 - mdpi.com
The disorder of Alzheimer's is marked by progressive pathophysiological
neurodegeneration. The amino acid peptides in the amyloid plaques found in the brains of …

A natural protein based platform for the delivery of temozolomide acid to glioma cells

DO Helal, N Rouatbi, S Han, JTW Wang… - European Journal of …, 2021 - Elsevier
Glioblastoma is one of the most difficult to treat cancers with poor prognosis and survival of
around one year from diagnosis. Effective treatments are desperately needed. This work …

Applications and advancements of polysaccharide-based nanostructures for enhanced drug delivery

AF Kareemi, S Likhitkar - Colloids and Surfaces B: Biointerfaces, 2024 - Elsevier
Growing demand for highly effective, site-specific delivery of pharmaceuticals and
nutraceuticals using nano-sized carriers has prompted increased scrutiny of carrier …

Small Scale, Big Impact: Nanotechnology-Enhanced Drug Delivery for Brain Diseases

K Miao, X Xia, Y Zou, B Shi - Molecular Pharmaceutics, 2024 - ACS Publications
Central nervous system (CNS) diseases, ranging from brain cancers to neurodegenerative
disorders like dementia and acute conditions such as strokes, have been heavily burdening …

[HTML][HTML] To see or not to see: In vivo nanocarrier detection methods in the brain and their challenges

AC Wehn, E Krestel, BN Harapan… - Journal of Controlled …, 2024 - Elsevier
Nanoparticles have a great potential to significantly improve the delivery of therapeutics to
the brain and may also be equipped with properties to investigate brain function. The brain …