Improving quality and quantity of life for childhood cancer survivors globally in the twenty-first century
The contributions of cooperative groups to performing large-cohort clinical trials and long-
term survivorship studies have facilitated advances in treatment, supportive care and …
term survivorship studies have facilitated advances in treatment, supportive care and …
Recent progress in the treatment of cancer in children
E Butler, K Ludwig, HL Pacenta… - CA: a cancer journal …, 2021 - Wiley Online Library
Although significant improvements have been made in the outcomes of children with cancer,
the pace of improvement has slowed in recent years as the limits of therapy intensification …
the pace of improvement has slowed in recent years as the limits of therapy intensification …
Diagnostic yield of clinical tumor and germline whole-exome sequencing for children with solid tumors
DW Parsons, A Roy, Y Yang, T Wang, S Scollon… - JAMA …, 2016 - jamanetwork.com
Importance Whole-exome sequencing (WES) has the potential to reveal tumor and germline
mutations of clinical relevance, but the diagnostic yield for pediatric patients with solid …
mutations of clinical relevance, but the diagnostic yield for pediatric patients with solid …
Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells
M Vinci, A Burford, V Molinari, K Kessler, S Popov… - Nature medicine, 2018 - nature.com
The failure to develop effective therapies for pediatric glioblastoma (pGBM) and diffuse
intrinsic pontine glioma (DIPG) is in part due to their intrinsic heterogeneity. We aimed to …
intrinsic pontine glioma (DIPG) is in part due to their intrinsic heterogeneity. We aimed to …
Prediction of ischemic heart disease and stroke in survivors of childhood cancer
EJ Chow, Y Chen, MM Hudson, EAM Feijen… - Journal of Clinical …, 2018 - ascopubs.org
Purpose We aimed to predict individual risk of ischemic heart disease and stroke in 5-year
survivors of childhood cancer. Patients and Methods Participants in the Childhood Cancer …
survivors of childhood cancer. Patients and Methods Participants in the Childhood Cancer …
Treatment of pediatric low-grade gliomas
SF Sait, AM Giantini-Larsen, KR Tringale… - Current neurology and …, 2023 - Springer
Abstract Purpose of Review Pediatric low-grade gliomas and glioneuronal tumors (pLGG)
account for approximately 30% of pediatric CNS neoplasms, encompassing a …
account for approximately 30% of pediatric CNS neoplasms, encompassing a …
[HTML][HTML] Medulloblastoma in the modern era: review of contemporary trials, molecular advances, and updates in management
MA Lazow, JD Palmer, M Fouladi, R Salloum - Neurotherapeutics, 2022 - Elsevier
Critical discoveries over the past two decades have transformed our understanding of
medulloblastoma from a single entity into a clinically and biologically heterogeneous …
medulloblastoma from a single entity into a clinically and biologically heterogeneous …
Pediatric patients demonstrate progressive T1-weighted hyperintensity in the dentate nucleus following multiple doses of gadolinium-based contrast agent
DR Roberts, AR Chatterjee… - American Journal …, 2016 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: While there have been recent reports of brain retention of
gadolinium following gadolinium-based contrast agent administration in adults, a …
gadolinium following gadolinium-based contrast agent administration in adults, a …
Modern radiotherapy for pediatric brain tumors
NJ DeNunzio, TI Yock - Cancers, 2020 - mdpi.com
Cancer is a leading cause of death in children with tumors of the central nervous system, the
most commonly encountered solid malignancies in this population. Radiotherapy (RT) is an …
most commonly encountered solid malignancies in this population. Radiotherapy (RT) is an …
Temozolomide with irinotecan versus temozolomide, irinotecan plus bevacizumab for recurrent medulloblastoma of childhood: Report of a COG randomized Phase II …
AS Levy, M Krailo, S Chi, D Villaluna… - Pediatric blood & …, 2021 - Wiley Online Library
Background: Approximately 30% of children with medulloblastoma (MB) experience
recurrence, which is usually incurable. This study compared the overall survival (OS) of …
recurrence, which is usually incurable. This study compared the overall survival (OS) of …