Context: Olive [Olea europaea L.(Oleaceae)] is a long-lived evergreen tree that is
widespread in different parts of the world. Objective: Olive oil has been reported to relieve …

Over 75% of depressed patients suffer from painful symptoms predicting a greater severity
and a less favorable outcome of depression. Imaging, anatomical and functional studies …

The role of serotonin (5-HT) in nociception will vary according to the subtypes of receptors
activated. When administered peripherally, it induces pain in humans and in rats by …

Tramadol, a central analgesic acting on serotonin neurotransmission, is often co-used with
ondansetron, a 5-HT3 antagonist, for the management of postoperative pain to decrease …

Background. Monoaminergic pathways, impinging an adrenergic and 5-HT3 serotonin
receptors, modulate nociceptive transmission, but their mechanisms and interactions has not …

Aim: Somatoform pain disorder is characterized by persistent and chronic pain at one or
more sites without an associated general medical condition and in which psychological …

It is well-known that the exposure of rodents to threatening environments [eg, the open arm
of the elevated-plus maze (EPM)] elicits pain inhibition. Systemic and/or intracerebral [eg …

Paclitaxel is widely used in cancer chemotherapy for the treatment of solid tumors, but it
frequently causes peripheral neuropathy. Milnacipran, a serotonin/noradrenaline reuptake …

A previous study reported the in vivo anti-inflammatory and antinociceptive activities of
essential oil of the underground stem bark of Duguetia furfuracea, termed EODf. This study …

PURPOSE: Many studies have reported both a gender difference in the rates of depression
and its treatment by using any of the widely used antidepressant drug groups. Some studies …