Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis
worldwide. It is a leading cause of chronic kidney disease and progresses to end-stage …

IgA nephropathy (IgAn), defined by the pre dominant de position of IgA in the glomerular
mesangium, is the most common form of GN throughout the world. However, its incidence …

B cell activation factor of the TNF family (BAFF) is a potent B cell survival factor. BAFF
overexpressing transgenic mice (BAFF-Tg mice) exhibit features of autoimmune disease …

The TNF family member a proliferation-inducing ligand (APRIL; also known as TNFSF13),
produced by myeloid cells, participates in the generation and survival of antibody–producing …

Background Recent studies have shown that galactose-deficient IgA1 (GdIgA1) has an
important role in the pathogenesis of IgA nephropathy (IgAN). Although emerging data …

Background The efficacy of tonsillectomy in immunoglobulin A nephropathy (IgAN) remains
controversial. The aim of the study was to conduct a randomized controlled trial to evaluate …

Abstract Background. Patients with IgA nephropathy (IgAN) often show aggravation of renal
injury with macroscopic hematuria after mucosal infections, especially tonsillitis. We …

Abstract ddY mice spontaneously develop IgA nephropathy (IgAN) with a variable age of
disease onset. Establishing a model with early-onset IgAN could aid the investigation of …

Although a major source of genetic variation, copy number variations (CNVs) and their
involvement in disease development have not been well studied. Immunoglobulin A …

Chronic kidney disease (CKD) is a worldwide public health problem that affects millions of
people from all racial and ethnic groups. Although CKD is not one specific disease, it is a …