Zwitterionic targeting doxorubicin-loaded micelles assembled by amphiphilic dendrimers with enhanced antitumor performance

L Zhang, Q Guo, R Zheng, Q Yu, Y Liang, G Ma, Q Li… - Langmuir, 2023 - ACS Publications
Chemotherapy is the main method of treating malignant tumors in clinical treatment.
However, the commonly used chemotherapeutic drugs have the disadvantages of high …

[PDF][PDF] An amphiphilic ruthenium polymetallodrug for combined photodynamic therapy and photochemotherapy in vivo

W Sun, S Li, B Häupler, J Liu, S Jin, W Steffen… - Adv. Mater, 2017 - d-nb.info
The success of several FDA-approved platinum anticancer drugs has stimulated increasing
interest in the development of new metallodrugs.[1] Ruthenium (Ru) complexes are potential …

Recent advances in stimuli‐responsive theranostic systems with aggregation‐induced emission characteristics

JJ Hu, W Jiang, L Yuan, C Duan, Q Yuan, Z Long… - …, 2021 - Wiley Online Library
Theranostic systems by integrating the tumor imaging and tumor therapeutic capabilities into
one platform have attracted numerous attentions from worldwide researchers. Despite the …

A dual targeting dendrimer-mediated siRNA delivery system for effective gene silencing in cancer therapy

Y Dong, T Yu, L Ding, E Laurini, Y Huang… - Journal of the …, 2018 - ACS Publications
Small interfering RNA (siRNA) is emerging as a novel therapeutic for treating various
diseases, provided a safe and efficient delivery is available. In particular, specific delivery to …

Protein-based nanomedicine for therapeutic benefits of cancer

Q Zhang, J Zhang, J Song, Y Liu, X Ren, Y Zhao - ACS nano, 2021 - ACS Publications
Proteins, a type of natural biopolymer that possess many prominent merits, have been
widely utilized to engineer nanomedicine for fighting against cancer. Motivated by their ever …

Overcoming multidrug resistance in cancer: Recent progress in nanotechnology and new horizons

M Majidinia, M Mirza‐Aghazadeh‐Attari, M Rahimi… - IUBMB …, 2020 - Wiley Online Library
Multidrug resistance (MDR), defined as the ability of cancer cells to gain resistance to both
conventional and novel chemotherapy agents, is an important barrier in treating …

An amphiphilic dendrimer as a light-activable immunological adjuvant for in situ cancer vaccination

Y Wang, N Gong, C Ma, Y Zhang, H Tan, G Qing… - Nature …, 2021 - nature.com
Immunological adjuvants are essential for successful cancer vaccination. However,
traditional adjuvants have some limitations, such as lack of controllability and induction of …

Poly (amidoamine) dendrimers: Covalent and supramolecular synthesis

Z Lyu, L Ding, AYT Huang, CL Kao, L Peng - Materials Today Chemistry, 2019 - Elsevier
Dendrimers, a class of synthetic macromolecules which are notable for their well-defined
ramified structures and unique multivalent cooperativity, hold great promise for developing …

Nanoparticle-based drug delivery systems to overcome gastric cancer drug resistance

K Nejati, M Rastegar, F Fathi, M Dadashpour… - Journal of Drug Delivery …, 2022 - Elsevier
Gastric cancer (GC) results from deregulated cell growth in the stomach. Despite significant
efforts and recent advancements in the treatment of gastric cancer, it remains a life …

Smart transformable nanomedicines for cancer therapy

Y Wang, S Li, X Wang, Q Chen, Z He, C Luo, J Sun - Biomaterials, 2021 - Elsevier
Despite that great progression has been made in nanoparticulate drug delivery systems
(nano-DDS), multiple drug delivery dilemmas still impair the delivery efficiency of …