A non-cytotoxic dendrimer with innate and potent anticancer and anti-metastatic activities

S Shao, Q Zhou, J Si, J Tang, X Liu, M Wang… - Nature Biomedical …, 2017 - nature.com
The structural perfection and multivalency of dendrimers have made them useful for
biodelivery and bioactivity via peripheral functionalization and the modulation of core …

A transformable chimeric peptide for cell encapsulation to overcome multidrug resistance

C Zhang, LH Liu, WX Qiu, YH Zhang, W Song, L Zhang… - Small, 2018 - Wiley Online Library
Multidrug resistance (MDR) remains one of the biggest obstacles in chemotherapy of tumor
mainly due to P‐glycoprotein (P‐gp)‐mediated drug efflux. Here, a transformable chimeric …

Systemic dendrimer-drug treatment of ischemia-induced neonatal white matter injury

E Nance, M Porambo, F Zhang, MK Mishra… - Journal of Controlled …, 2015 - Elsevier
Extreme prematurity is a major risk factor for perinatal and neonatal brain injury, and can
lead to white matter injury that is a precursor for a number of neurological diseases …

An emerging class of amphiphilic dendrimers for pharmaceutical and biomedical applications: Janus amphiphilic dendrimers

DR Sikwal, RS Kalhapure, T Govender - European Journal of …, 2017 - Elsevier
In recent years, a new class of dendrimer, known as Janus dendrimers (JDs), has attracted
much attention due to their different structures and properties to the conventional symmetric …

An Accelerated Modular-Orthogonal Ni-Catalyzed Methodology to Symmetric and Nonsymmetric Constitutional Isomeric AB2 to AB9 Dendrons Exhibiting …

V Percec, S Wang, N Huang, BE Partridge… - Journal of the …, 2021 - ACS Publications
Five libraries of natural and synthetic phenolic acids containing five AB3, ten constitutional
isomeric AB2, one AB4, and one AB5 were previously synthesized and reported by our …

Cationic micelle: A promising nanocarrier for gene delivery with high transfection efficiency

H Wang, S Ding, Z Zhang, L Wang… - The journal of gene …, 2019 - Wiley Online Library
Micelles have demonstrated an excellent ability to deliver several different types of
therapeutic agents, including chemotherapy drugs, proteins, small‐interfering RNA and …

3D-printed NIR-responsive bullets as multifunctional nanodrug platforms for image-guided local chemo-photothermal therapy

G Han, H Lee, JM Kang, JH Park, E Lee, ES Lee… - Chemical Engineering …, 2023 - Elsevier
Multimodal cancer treatment that combines anticancer drug delivery with other therapeutic
strategies, such as photothermal therapy, has shown enormous potential for biomedical …

Transferrin protein corona-modified CuGd core–shell nanoplatform for tumor-targeting photothermal and chemodynamic synergistic therapies

X Qi, G Wang, P Wang, Y Pei, C Zhang… - … Applied Materials & …, 2022 - ACS Publications
Herein, we developed a novel transferrin protein corona (Tpc)-modified CuGd nanoplatform
(Tpc-CuGd) for tumor-targeting photothermal (PT) and chemodynamic synergistic therapy. In …

From supramolecular vesicles to micelles: controllable construction of tumor‐targeting nanocarriers based on host–guest interaction between a pillar [5] arene‐based …

XY Hu, L Gao, S Mosel, M Ehlers, E Zellermann… - Small, 2018 - Wiley Online Library
The targeting ability, drug‐loading capacity, and size of the drug nanocarriers are crucial for
enhancing the therapeutic index for cancer therapy. Herein, the morphology and size …

Self-sorting and coassembly of fluorinated, hydrogenated, and hybrid Janus dendrimers into dendrimersomes

Q Xiao, JD Rubien, Z Wang, EH Reed… - Journal of the …, 2016 - ACS Publications
The modular synthesis of a library containing seven self-assembling amphiphilic Janus
dendrimers is reported. Three of these molecules contain environmentally friendly chiral …