The vascular endothelium is a dynamic, functionally complex organ, modulating multiple
biological processes, including vascular tone and permeability, inflammatory responses …

Abstract N-acetyl-l-cysteine (NAC) has long been used therapeutically for the treatment of
acetaminophen (paracetamol) overdose, acting as a precursor for the substrate (l-cysteine) …

Fruits, vegetables, and other food items contain phytochemicals or secondary metabolites
which may be considered non-essential nutrients but have medicinal importance. These …

Hypertension is characterized by structural and functional changes in blood vessels that
travel with increased arterial stiffness, vascular inflammation, and endothelial dysfunction …

Platelets are central to inflammation-related manifestations of cardiovascular diseases
(CVD) such as atherosclerosis. Platelet-activating factor (PAF), thrombin, thromboxane A 2 …

Bioactive peptides derived from milk proteins are food components that, in addition to their
nutritional value, retain many biological properties and have therapeutic effects in several …

Oxidative stress is a key feature of the atherothrombotic process involved in the etiology of
heart attacks, ischemic strokes, and peripheral arterial disease. It stands to reason that …

The etiology of Alzheimer's disease (AD) remains unclear. The emerging view is that
cerebrovascular dysfunction is a feature not only of cerebrovascular diseases, such as …

Polyphenols are widely regarded to have a wide range of health‐promoting qualities,
including beneficial effects on cardiovascular disease. Historically, the benefits have been …

Rationale: Accumulating evidence supports a role of adaptive immunity and particularly T
cells in the pathogenesis of hypertension. Formation of memory T cells, which requires the …