Tissues stiffen during aging and during the pathological progression of cancer, fibrosis, and
cardiovascular disease. Extracellular matrix stiffness is emerging as a prominent mechanical …

Pulmonary fibrosis (PF) is a growing clinical problem which can result in breathlessness or
respiratory failure and has an average life expectancy of 3 years from diagnosis …

Dynamic and heterogeneous interaction between tumor cells and the surrounding
microenvironment fuels the occurrence, progression, invasion, and metastasis of solid …

Idiopathic pulmonary fibrosis (IPF) is characterized by the transforming growth factor (TGF)-β–
dependent differentiation of lung fibroblasts into myofibroblasts, leading to excessive …

Pulmonary fibrosis is a chronic, progressive, incurable interstitial lung disease with high
mortality after diagnosis and remains a global public health problem. Despite advances and …

Background Idiopathic pulmonary fibrosis (IPF) is a chronic progressive multifactorial
disease with limited therapeutic options. Glycosides based standardized fenugreek seed …

Idiopathic pulmonary fibrosis is a fatal interstitial lung disease characterized by the TGF-β
(transforming growth factor-β)–dependent differentiation of lung fibroblasts into …

Pericytes, resident fibroblasts, and mesenchymal stem cells are poorly described cell
populations. They have recently been characterized in much greater detail in rodent lungs …

Background Idiopathic pulmonary fibrosis is a progressive fibrotic lung disease that distorts
pulmonary architecture, leading to hypoxia, respiratory failure, and death. Diagnosis is …

Fibrosis is a pathologic condition characterized by excessive deposition of extracellular
matrix and chronic scaring that can affect every organ system. Organ fibrosis is associated …