Demineralized bone matrix (DBM) is an osteoconductive and osteoinductive commercial
biomaterial and approved medical device used in bone defects with a long track record of …

The emergence of the molecular triad osteoprotegerin (OPG)/Receptor Activator of NF-kB
(RANK)/RANK Ligand (RANKL) has helped elucidate a key signalling pathway between …

Large bony defects and non-unions are still a complication in trauma and orthopedic
surgery. Treatment strategies include the use of autogenous materials (iliac crest), allogenic …

The problem of bone regeneration has engaged both physicians and scientists since the
beginning of medicine. Not only can bone heal itself following most injuries, but when it …

Besides autografts, allografts, and synthetic materials, demineralized bone matrix (DBM) is
used for bone defect filling and treatment of non‐unions. Different DBM formulations are …

Study Design. Enzyme-linked immunosorbent assay was used to detect bone
morphogenetic proteins (BMPs) 2, 4, and 7 in 9 commercially available (“off the shelf”) …

Tissue engineering and regenerative medicine have shown potential in the repair and
regeneration of tissues and organs via the use of engineered biomaterials and scaffolds …

The present study evaluated the human mesenchymal stem cells (hMSCs) isolated from skin
(hSMSC), bone marrow (hBMSC) and dental follicle (hDFMSC) tissues on their in vitro and …

Poly (lactide-co-glycolic acid)(PLGA) has been widely applied to tissue engineering as a
good biocompatible material because of its biodegradability and nontoxic metabolites, but …

Matrix vesicles (MVs) are well positioned in the growth plate to serve as a carrier of
morphogenetic information to nearby chondrocytes and osteoblasts. Bone morphogenetic …