Therapeutic strategies focusing on immune dysregulation and neuroinflammation in rosacea

KY Tu, CJ Jung, YH Shih, ALS Chang - Frontiers in Immunology, 2024 - frontiersin.org
Rosacea is a complex inflammatory condition characterized by papulopustular lesions and
erythema on the central face for which there is no cure. The development of rosacea is …

Subcutaneous adipose tissue: Implications in dermatological diseases and beyond

R Ziadlou, GN Pandian, J Hafner, CA Akdis, G Stingl… - Allergy, 2024 - Wiley Online Library
Subcutaneous adipose tissue (SAT) is the deepest component of the three‐layered
cutaneous integument. While mesenteric adipose tissue‐based immune processes have …

Insight into novel anti-mucormycosis therapies: investigation of new anti-mucormycosis laser-induced photodynamic therapy based on a sulphone bis-compound …

M Abdelraof, M Fikry, AH Hashem, ME El-Naggar… - RSC …, 2023 - pubs.rsc.org
For drug delivery applications, silica nanoemulsion encapsulated with organic compounds
are becoming increasingly more desirable. Therefore, the emphasis of this research was on …

Development of a multivariate predictive model for dapsone adverse drug events in people with leprosy under standard WHO multidrug therapy

ACGS de Araujo, MAVB Hacker… - PLoS Neglected …, 2024 - journals.plos.org
Background The occurrence of adverse drug events (ADEs) during dapsone (DDS)
treatment in patients with leprosy can constitute a significant barrier to the successful …

Anti-inflammatory and protective effects of Aripiprazole on TNBS-Induced colitis and associated depression in rats: Role of kynurenine pathway

A Mohammadgholi-Beiki, M Sheibani… - International …, 2024 - Elsevier
Background The prevalence of depression is higher in patients with inflammatory bowel
disease (IBD) than in the general population. Inflammatory cytokines and the kynurenine …

Zhumeria majdae essential oil attenuates TNBS-induced colitis in rats by regulating inflammatory and apoptotic pathways

H Aghamiri, A Mohammadgholi-Beiki… - …, 2024 - Springer
Background and aim Zhumeria majdae, a unique native plant of southern Iran, has been
traditionally used to treat various health issues. Preclinical studies suggest its therapeutic …

Evaluating the protective effect of dapsone on experimental osteoarthritis models induced by MIA in male rats

K Nazari, S Hosseindoost, AR Dehpour… - Journal of Pharmacy …, 2024 - academic.oup.com
Objectives Osteoarthritis, a degenerative condition that results in significant morbidity, is
typically managed with treatments aimed at symptom relief rather than addressing the …

[HTML][HTML] IPIAD-an augmentation regimen added to standard treatment of pancreatic ductal adenocarcinoma using already-marketed repurposed drugs irbesartan …

RE Kast - Oncoscience, 2024 - ncbi.nlm.nih.gov
This short note presents the data and rationale for adding five generic non-oncology drugs
from general medical practice to gemcitabine, nab-paclitaxel, a current standard cytotoxic …

Transcriptomic Analysis of Hub Genes Reveals Associated Inflammatory Pathways in Estrogen-Dependent Gynecological Diseases

EC Pasamba, MA Orda, BHA Villanueva, PW Tsai… - Biology, 2024 - mdpi.com
Simple Summary Gynecological diseases still make up a large percentage of the overall
global disease burden. While oral contraceptives and gonadotropin-releasing hormone …

[HTML][HTML] Dapsone as a Current Option for the Treatment of Autoimmune Bullous Diseases with Autoimmunity to Non-Enzymes: A Retrospective Study from a Single …

MM Spałek, M Jałowska, N Welc… - Medicina, 2024 - mdpi.com
Background and Objectives: Dapsone (DP) is employed in the management of various skin
conditions, including autoimmune bullous diseases to non-enzymes (n-eAIBDs). This study …