The role of bacteria in cancer therapy–enemies in the past, but allies at present

S Song, MS Vuai, M Zhong - Infectious agents and cancer, 2018 - Springer
In recent decades, bacteria's therapeutic role has aroused attention in medicinal and
pharmaceutical research. While bacteria are considered among the primary agents for …

[HTML][HTML] Bacteria and bacterial derivatives as delivery carriers for immunotherapy

SR Kang, DH Nguyen, SW Yoo, JJ Min - Advanced Drug Delivery Reviews, 2022 - Elsevier
There is growing interest in the role of microorganisms in human health and disease, with
evidence showing that new types of biotherapy using engineered bacterial therapeutics …

Suicide gene therapy in cancer: where do we stand now?

S Duarte, G Carle, H Faneca, MCP de Lima… - Cancer letters, 2012 - Elsevier
Suicide gene therapy is based on the introduction into tumor cells of a viral or a bacterial
gene, which allows the conversion of a non-toxic compound into a lethal drug. Although …

Emerging applications of bacteria as antitumor agents

VC Kalia, SKS Patel, BK Cho, TK Wood… - Seminars in Cancer …, 2022 - Elsevier
Bacteria are associated with the human body and colonize the gut, skin, and mucous
membranes. These associations can be either symbiotic or pathogenic. In either case …

[HTML][HTML] Hybrid biomicromotors

L Schwarz, M Medina-Sánchez… - Applied Physics Reviews, 2017 - pubs.aip.org
Micromotors are devices that operate at the microscale and convert energy to motion. Many
micromotors are microswimmers, ie, devices that can move freely in a liquid at a low …

Microbes as medicines: harnessing the power of bacteria in advancing cancer treatment

SS Sawant, SM Patil, V Gupta, NK Kunda - International journal of …, 2020 - mdpi.com
Conventional anti-cancer therapy involves the use of chemical chemotherapeutics and
radiation and are often non-specific in action. The development of drug resistance and the …

[HTML][HTML] Live-attenuated bacterial vectors: tools for vaccine and therapeutic agent delivery

IYC Lin, TTH Van, PM Smooker - Vaccines, 2015 - mdpi.com
Genetically attenuated microorganisms, including pathogenic and commensal bacteria, can
be engineered to carry and deliver heterologous antigens to elicit host immunity against …

Selenium enrichment of lactic acid bacteria and bifidobacteria: A functional food perspective

SD Pophaly, P Singh, H Kumar, SK Tomar… - Trends in Food Science & …, 2014 - Elsevier
Highlights•Accumulation and biotransformation of selenium by lactic acid
bacteria.•Implications of selenium enrichment of probiotics and gut microbiota.• …

The role of bacterial toxins and spores in cancer therapy

LR Weerakkody, C Witharana - Life sciences, 2019 - Elsevier
Cancer is one of the leading causes of human death worldwide. Conventional anticancer
therapies are ineffective in treating cancer patients due to various reasons. Thus, more …

New generation of plasmid backbones devoid of antibiotic resistance marker for gene therapy trials

G Vandermeulen, C Marie, D Scherman, V Préat - Molecular Therapy, 2011 - cell.com
Since it has been established that the injection of plasmid DNA can lead to an efficient
expression of a specific protein in vivo, nonviral gene therapy approaches have been …