Diabetic foot ulcers (DFUs) are a devastating complication for diabetic patients that have
debilitating effects and can ultimately lead to limb amputation. Healthy wounds progress …

Cardiac organoids are 3-dimensional (3D) structures composed of tissue or niche-specific
cells, obtained from diverse sources, encapsulated in either a naturally derived or synthetic …

Cardiovascular diseases are caused by hereditary factors, environmental conditions, and
medication-related issues. On the other hand, the cardiotoxicity of drugs should be …

Microfluidic lab-on-a-chip technologies enable the analysis and manipulation of small fluid
volumes and particles at small scales and the control of fluid flow and transport processes at …

Microphysiological systems (MPS) are drawing increasing interest from academia and from
biomedical industry due to their improved capability to capture human physiology. MPS offer …

Stem cell-derived β cells offer an alternative to primary islets for biomedical discoveries as
well as a potential surrogate for islet transplantation. The expense and challenge of …

Blood-neural barriers regulate nutrient supply to neuronal tissues and prevent neurotoxicity.
In particular, the inner blood-retinal barrier (iBRB) and blood–brain barrier (BBB) share …

Abstract Models of heart disease and drug responses are increasingly based on human
pluripotent stem cells (hPSCs) since their ability to capture human heart (dys-) function is …

Vascular diseases are the underlying pathology in many life-threatening illnesses. Human
cellular and molecular mechanisms involved in angiogenesis are complex and difficult to …

Background The composite transplantation of a split-thickness skin graft (STSG) combined
with an acellular dermal matrix (ADM) is a promising repair method for full-thickness skin …