Childhood maltreatment is the most important preventable risk factor for psychiatric
disorders. Maltreated individuals typically develop psychiatric disorders at an earlier age …

Despite a longstanding and widespread influence of the diagnostic approach to mental ill
health, there is an emerging and growing consensus that such psychiatric nosologies may …

Two extant frameworks–the harshness-unpredictability model and the threat-deprivation
model–attempt to explain which dimensions of adversity have distinct influences on …

Background Transdiagnostic processes confer risk for multiple types of psychopathology
and explain the co-occurrence of different disorders. For this reason, transdiagnostic …

An extensive literature on childhood adversity and neurodevelopment has emerged over the
past decade. We evaluate two conceptual models of adversity and neurodevelopment—the …

A large body of evidence has demonstrated that exposure to childhood maltreatment at any
stage of development can have long-lasting consequences. It is associated with a marked …

In both child and adult psychiatry, empirical evidence has now accrued to suggest that a
single dimension is able to measure a person's liability to mental disorder, comorbidity …

Introduction: Adverse childhood experiences (ACE) such as sexual and physical abuse or
neglect are frequent in childhood and constitute a massive stressor with long-lasting …

Substantial evidence from various studies suggests a preeminent role for early adverse
experiences in the development of psychopathology. The most recent studies reviewed here …

Background Child maltreatment is a global public health issue that encompasses physical
abuse, sexual abuse, emotional abuse, neglect, and exposure to intimate partner violence …