Brain edema is a potentially fatal pathological state that occurs after brain injuries such as
stroke and head trauma. In the edematous brain, excess accumulation of extracellular fluid …

Faraci, Frank M., and Donald D. Heistad. Regulation of the Cerebral Circulation: Role of
Endothelium and Potassium Channels. Physiol. Rev. 78: 53–97, 1998.—Several new …

Current strategies to limit the extent of injury in acute renal failure are based on extensive
studies that identified cellular and molecular mechanisms of acute kidney injury. Despite …

Extracellular stimuli induce cytoskeleton reorganization (stress-fiber formation) in cells and
Ca2+ sensitization in intact smooth muscle preparations by activating signaling pathways …

Endothelin receptor antagonists have been proposed for the treatment of a variety of
disorders in which the endothelins may act as pathogenic mediators, such as congestive …

Aging per se is associated with abnormalities of the vascular wall linked to both structural
and functional changes that can take place at the level of the extracellular matrix, the …

Objective Sesamin has been proved to be antihypertensive. Nitric oxide (NO) is the most
important vascular relaxing factor that is regulated in endothelium. Endothelin-1 (ET-1) is …

The contractile response to endothelin-1 (ET-1) appears to be modulated by the relative
density of ETA and ETBreceptors. To determine the effects of gender on the distribution of …

Increased evidence has shown that endothelin‐1 (ET‐1) derived from the arterial cells is
involved in the development of atherosclerosis. ET‐1 and ET receptors are upregulated in …

Prostate cancer is the second most common cancer and the second leading cause of cancer
death in men. However, prostate cancer can be effectively treated and cured, if it is …