Traditional Chinese Medicine has great potential as candidate drugs for lung cancer: A review

Z Wei, J Chen, F Zuo, J Guo, X Sun, D Liu… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance With high mortality and morbidity rates, lung cancer (LC)
has become one of the major threats to human health. The treatment strategies for LC …

Targeting the interplay of autophagy and ROS for cancer therapy: An updated overview on phytochemicals

L Dong, J He, L Luo, K Wang - Pharmaceuticals, 2023 - mdpi.com
Autophagy is an evolutionarily conserved self-degradation system that recycles cellular
components and damaged organelles, which is critical for the maintenance of cellular …

Dihydroartemisinin suppresses the tumorigenesis and cycle progression of colorectal cancer by targeting CDK1/CCNB1/PLK1 signaling

YC Yi, R Liang, XY Chen, HN Fan, M Chen… - Frontiers in …, 2021 - frontiersin.org
Dihydroartemisinin (DHA), a well-known antimalarial drug, has been widely investigated for
its antitumor effects in multiple malignancies. However, its effects and regulatory …

Evaluation of the phytochemicals and antioxidant activity of Lophatherum gracile Brongn based on chemical fingerprinting by HPLC with electrochemical detection

P Zhang, Z Chun, Q Shao, L Fu, Y Luo… - Journal of …, 2021 - Wiley Online Library
A combinative method using high‐performance liquid chromatography‐electrochemical
detection for fingerprinting and quantitative analysis was developed and successfully …

Cancer protective role of selected dietary polyphenols via modulating Keap1/Nrf2/ARE and interconnected signaling pathways

MA Islam, MM Medha, AU Nahar, MA Al Fahad… - Nutrition and …, 2023 - Taylor & Francis
The Kelch-like ECH associated protein 1 (Keap1)/nuclear factor erythroid 2-related factor 2
(Nrf2)/antioxidant response elements (ARE) signaling pathway is considered a master …

Bio-mediated zinc oxide nanoparticles through tea residue: ecosynthesis, characterizations, and biological efficiencies

TE Mathizhagan, V Subramaniyan, S Renganathan… - Sustainability, 2022 - mdpi.com
Recent advances in nanotechnology have placed a major emphasis on environmentally
friendly processes that encourage sustainable growth by using moderate reaction conditions …

A mechanism of isoorientin-induced apoptosis and migration inhibition in gastric cancer AGS cells

T Zhang, YH Xiu, H Xue, YN Li, JL Cao, WS Hou, J Liu… - Pharmaceuticals, 2022 - mdpi.com
Isoorientin (ISO) is a flavonoid compound containing a luteolin structure, which can induce
autophagy in some tumor cells. This study investigated the impact of ISO in gastric cancer …

Synthesis, structure characterization, and antioxidant and antibacterial activity study of iso-orientin–zinc complex

X Wang, S He, L Yuan, H Deng… - Journal of Agricultural and …, 2021 - ACS Publications
Flavonoid–metal complexes possess more effective functional properties than flavonoids.
However, the research of iso-orientin (Iso)–metal complex has rarely been reported. In this …

Isoorientin ameliorates OVA-induced asthma in a murine model of asthma

S Liang, Y Zhao, G Chen… - Experimental Biology and …, 2022 - journals.sagepub.com
Allergic asthma which is induced by ovalbumin (OVA) is a chronic airway inflammation
disease. Isoorientin (Iso) is a natural C-glucosyl flavone with many biological properties. We …

Isoorientin suppresses sepsis-induced acute lung injury in mice by activating an EPCR-dependent JAK2/STAT3 pathway

M Hu, J Yang, Y Xu - Journal of Molecular Histology, 2022 - Springer
Sepsis is a systemic inflammatory syndrome, and acute lung injury (ALI) is one of the most
common fatal complications of sepsis. Isoorientin (ISO) exerts a momentous role in the …