Serotonin reuptake inhibitor antidepressants, including selective serotonin reuptake
inhibitors (SSRIs; ie, citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, and …

In the last decade the serotonin transporter gene promoter polymorphism (5-HTTLPR) was
likely the most studied genetic variant as predictor of antidepressant response. Nevertheless …

This systematic review summarizes pharmacogenetic studies on antidepressant response
and side effects. Out of the 17 genes we reviewed, 8 genes were entered into the meta …

Discovered and crystallized over sixty years ago, serotonin's important functions in the brain
and body were identified over the ensuing years by neurochemical, physiological and …

Personalized medicine—the adaptation of therapies based on an individual's genetic and
molecular profile—is one of the most promising aspects of modern medicine. The …

Context TheHTTLPR, a functional polymorphism of the serotonin transporter gene solute
carrier family 6 (neurotransmitter transporter, serotonin), member 4 (SLC6A4), promoter …

BACKGROUND: The serotonin transporter gene-linked polymorphic region (5-HTTLPR) has
been proposed as a predictor of antidepressant response. Insertion or deletion of a 44-base …

Major depressive disorder (MDD) is a heritable disease with a heavy personal and socio-
economic burden. Antidepressants of different classes are prescribed to treat MDD, but …

Major depressive disorder (MDD) is an emergent cause of personal and socio‐economic
burden, both for the high prevalence of the disorder and the unsatisfying response rate of …

While antidepressants are widely used to treat major depressive disorder and anxiety
disorders, only half of the patients will respond to antidepressant treatment and only a third …