The effect of oral polio vaccine at birth on infant mortality: a randomized trial

N Lund, A Andersen, ASK Hansen… - Clinical Infectious …, 2015 - academic.oup.com
Background. Routine vaccines may have nonspecific effects on mortality. An observational
study found that OPV given at birth (OPV0) was associated with increased male infant …

Unravelling the nature of non-specific effects of vaccines—A challenge for innate immunologists

KJ Jensen, CS Benn, R van Crevel - Seminars in immunology, 2016 - Elsevier
Epidemiological observations have shown that vaccines can influence morbidity and
mortality more than can be ascribed to target-disease immunity. A growing number of …

Oral polio vaccination and hospital admissions with non-polio infections in Denmark: nationwide retrospective cohort study

S Sørup, LG Stensballe, TG Krause… - Open forum …, 2016 - academic.oup.com
Background. Live vaccines may have nonspecific beneficial effects on morbidity and
mortality. This study examines whether children who had the live-attenuated oral polio …

Stopping oral polio vaccine (OPV) after defeating poliomyelitis in low-and middle-income countries: harmful unintended consequences? Review of the nonspecific …

P Aaby, S Nielsen, AB Fisker… - Open Forum …, 2022 - academic.oup.com
Background The live vaccines bacille Calmette-Guérin (BCG) and measles vaccine have
beneficial nonspecific effects (NSEs) reducing mortality, more than can be explained by …

[HTML][HTML] Campaigns with oral polio vaccine may lower mortality and create unexpected results

CS Benn, LH Jacobsen, AB Fisker, A Rodrigues… - Vaccine, 2017 - Elsevier
Abstract Three studies from Guinea-Bissau found conflicting effects of OPV-at-birth (OPV0)
on child survival. One study from 2004 suggested excess male mortality among children …

The nature and ethics of natural experiments

A Dawson, J Sim - Journal of medical ethics, 2015 - jme.bmj.com
Natural experiments are an important methodology often used to answer research questions
that would, otherwise, be impossible to address, or employed because of ethical concerns …

Adverse events following immunization with oral poliovirus in Kinshasa, Democratic Republic of Congo: preliminary results

D Nzolo, MN Aloni, TM Ngamasata… - … and Global Health, 2013 - Taylor & Francis
Aim: We investigated the nature and frequency of adverse events following immunization
(AEFI) associated with oral polio vaccines (OPV) in the general population in Kinshasa …

Sex differences in outcomes of infections and vaccinations in under five-year-old children

KL Flanagan, KJ Jensen - Sex and gender differences in infection and …, 2015 - Springer
It is evident that human male and female children differ in their outcomes following infectious
challenge and vaccination. This chapter explores some of the evidence for this in children< …

[HTML][HTML] The immunological effects of oral polio vaccine provided with BCG vaccine at birth: a randomised trial

KJ Jensen, HS Karkov, N Lund, A Andersen… - Vaccine, 2014 - Elsevier
Background Vaccines may have non-specific effects. An observational study from Guinea-
Bissau suggested that oral polio vaccine at birth (OPV0) provided with Bacillus Calmette …

Efeitos não específicos das vacinas: revisão rápida dos estudos realizados nos países africanos de língua oficial portuguesa

I Fronteira - Anais do Instituto de Higiene e Medicina Tropical, 2022 - anaisihmt.com
Introdução: Algumas vacinas parecem ter também efeitos para além daqueles nas
doenças para as quais foram desenhadas, denominados de efeitos não específicos …