[HTML][HTML] Vancomycin Resistance in Enterococcus and Staphylococcus aureus

G Li, MJ Walker, DMP De Oliveira - Microorganisms, 2022 - mdpi.com
Enterococcus faecalis, Enterococcus faecium and Staphylococcus aureus are both common
commensals and major opportunistic human pathogens. In recent decades, these bacteria …

Neisseria gonorrhoeae vaccines: a contemporary overview

E Williams, KL Seib, CK Fairley… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Neisseria gonorrhoeae infection is an important public health issue, with an annual global
incidence of 87 million. N. gonorrhoeae infection causes significant morbidity and can have …

[HTML][HTML] The promising potential of reverse vaccinology-based next-generation vaccine development over conventional vaccines against antibiotic-resistant bacteria

K Khalid, CL Poh - Vaccines, 2023 - mdpi.com
The clinical use of antibiotics has led to the emergence of multidrug-resistant (MDR)
bacteria, leading to the current antibiotic resistance crisis. To address this issue, next …

[HTML][HTML] Toward a Shigella Vaccine: Opportunities and Challenges to Fight an Antimicrobial-Resistant Pathogen

MM Raso, V Arato, G Gasperini, F Micoli - International journal of …, 2023 - mdpi.com
Shigellosis causes more than 200,000 deaths worldwide and most of this burden falls on
Low-and Middle-Income Countries (LMICs), with a particular incidence in children under 5 …

Hit 'em Where It Hurts: Gram-Negative Bacterial Lipopolysaccharide as a Vaccine Target

AS Cross - Microbiology and Molecular Biology Reviews, 2023 - Am Soc Microbiol
Infections with antimicrobial-resistant (AMR) bacteria pose an increasing threat to the ability
to perform surgical procedures, organ transplantation, and treat cancer among many other …

[HTML][HTML] Vaccination is an integral strategy to combat antimicrobial resistance

LP Mullins, E Mason, K Winter, M Sadarangani - PLoS Pathogens, 2023 - journals.plos.org
Antimicrobial-resistant bacterial infections pose a significant challenge to health worldwide.
In 2019, there were an estimated 1.95 million deaths and 47.9 million lost disability-adjusted …

[HTML][HTML] Exploring the Role of GMMA Components in the Immunogenicity of a 4-Valent Vaccine against Shigella

F Mancini, R Alfini, V Caradonna, V Monaci… - International Journal of …, 2023 - mdpi.com
Shigellosis is the leading cause of diarrheal disease, especially in children of low-and
middle-income countries, and is often associated with anti-microbial resistance. Currently …

Acinetobacter baumannii subunit vaccines: recent progress and challenges

YT Lau, HS Tan - Critical reviews in microbiology, 2023 - Taylor & Francis
Acinetobacter baumannii is a Gram-negative, opportunistic pathogen that causes
nosocomial infection with a high mortality rate in immunocompromised individuals. With the …

Novel TLR4-Activating Vaccine Adjuvant Enhances the Production of Enterococcus faecium-binding Antibodies

AR Franco, O Sadones, A Romerio… - Journal of Medicinal …, 2024 - ACS Publications
Vaccines are one of the greatest achievements of modern medicine. Due to their safer
profile, the latest investigations usually focus on subunit vaccines. However, the active …

Economic and cost-effectiveness aspects of vaccines in combating antibiotic resistance

T Yemeke, HH Chen, S Ozawa - Human Vaccines & …, 2023 - Taylor & Francis
Antimicrobial resistance (AMR) is a global public health threat causing substantial morbidity
and mortality as well as significant economic costs. Vaccines can contribute to combating …