The role of zinc, copper, manganese and iron in neurodegenerative diseases

L Mezzaroba, DF Alfieri, ANC Simão, EMV Reiche - Neurotoxicology, 2019 - Elsevier
Metals are involved in different pathophysiological mechanisms associated with
neurodegenerative diseases (NDDs), including Alzheimer's disease (AD), Parkinson's …

Sex-specific neurotoxic effects of heavy metal pollutants: Epidemiological, experimental evidence and candidate mechanisms

M Gade, N Comfort, DB Re - Environmental research, 2021 - Elsevier
The heavy metals lead (Pb), mercury (Hg), and cadmium (Cd) are ubiquitous environmental
pollutants and are known to exert severe adverse impacts on the nervous system even at …

[PDF][PDF] Effect of heavy metals on fishes: Toxicity and bioaccumulation

P Garai, P Banerjee, P Mondal, NC Saha - J Clin Toxicol. S, 2021 - researchgate.net
Heavy metal pollution is a serious problem for the environment due to their toxicity,
persistency, bioaccumulation, and bio magnifications property. Heavy metal contamination …

[HTML][HTML] Metallobiology and therapeutic chelation of biometals (copper, zinc and iron) in Alzheimer's disease: Limitations, and current and future perspectives

KD Fasae, AO Abolaji, TR Faloye, AY Odunsi… - Journal of Trace …, 2021 - Elsevier
Background Alzheimer's disease (AD) is the most prevalent cause of cognitive impairment
and dementia worldwide. The pathobiology of the disease has been studied in the form of …

International analysis of sources and human health risk associated with trace metal contaminants in residential indoor dust

CF Isley, KL Fry, X Liu, GM Filippelli… - … science & technology, 2021 - ACS Publications
People spend increasing amounts of time at home, yet the indoor home environment
remains understudied in terms of potential exposure to toxic trace metals. We evaluated …

Selenium exposure and the risk of type 2 diabetes: a systematic review and meta-analysis

M Vinceti, T Filippini, KJ Rothman - European journal of epidemiology, 2018 - Springer
In 2007, supplementation with the trace element selenium in a trial was unexpectedly found
to be associated with an excess risk of type 2 diabetes. Given the concerns raised by these …

Oxidative stress, neuroinflammation and mitochondria in the pathophysiology of amyotrophic lateral sclerosis

E Obrador, R Salvador, R López-Blanch… - Antioxidants, 2020 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron (MN) disease. Its primary
cause remains elusive, although a combination of different causal factors cannot be ruled …

Metals and Alzheimer's disease: how far have we come in the clinic?

PA Adlard, AI Bush - Journal of Alzheimer's Disease, 2018 - content.iospress.com
It is estimated that by the year 2050 there will be more than 1.5 billion people globally over
the age of 65 years. Aging is associated with changes to a number of different cellular …

Technological advances in electrochemical biosensors for the detection of disease biomarkers

JH Kim, YJ Suh, D Park, H Yim, H Kim, HJ Kim… - Biomedical Engineering …, 2021 - Springer
With an increasing focus on health in contemporary society, interest in the diagnosis,
treatment, and prevention of diseases has grown rapidly. Accordingly, the demand for …

[HTML][HTML] Urban green space, tree canopy and 11-year risk of dementia in a cohort of 109,688 Australians

T Astell-Burt, MA Navakatikyan, X Feng - Environment International, 2020 - Elsevier
Introduction Urban greening is a climate change-related policy with considerable health
benefits. But do these benefits extend to prevention of dementia and, if so, which types of …