Stress urinary incontinence (SUI) is a distressing condition characterised by urine leakage
upon physical effort, coughing or sneezing and may affect up to half of adult women. Despite …

This report reviews literature on the role of information technology in two fields of science:
geoscience and bioscience. It was prepared as part of a National Science Foundation …

We develop a systematic methodology for pharmacokinetic (PK) modeling to predict drug
exposure profiles accurately. First, the number of compartments is determined by inspecting …

Drug development is a long and expensive process. It is often not until potential drug
candidates are administered to humans that accurate quantification of their pharmacokinetic …

In order to describe the behavior and activity of a drug in the body and give the quantitative
relationship between" input"(given dose or dosing regimen of the drug) and" output" data of …

This thesis describes a series of experimental studies (in vitro, ex vivo, in vivo) conducted
and integrated using modelling/scaling approaches to develop compartmental and …

Drug design through computer, a re Drug Design (CADD) technologies benefit of the CADD
is cost effectiv are used in CADD. There are differe energy minimization molecular do …

En la historiografía novohispana sobre la apropiación del suelo ha sido recurrente citar las
reales cédulas emitidas por el rey Felipe II en noviembre de 1591. Estas disposiciones …

1. Résumé Les modèles physiologiques toxicocinétiques (PBPK pour Physiologically-Based
PharmacoKinetic) permettent de décrire la biodistribution d'une substance (c'est-à-dire, son …

Problems in engineering, computational science, and the physical and biological sciences
are using increasingly sophisticated mathematical techniques. Thus, the bridge between the …