Sleep plays an essential role in all studied animals with a nervous system. However, sleep
deprivation leads to various pathological changes and neurobehavioral problems …

Aging is a complex and multifaceted process involving a variety of interrelated molecular
mechanisms and cellular systems. Phenotypically, the biological aging process is …

The impact of tau pathology on sleep microarchitecture features, including slow oscillations,
spindles, and their coupling, has been understudied, despite the proposed importance of …

Sleep deprivation (SD) has adverse effects on physical and mental health. Recently
increasing attention has been given to SD in the early-life stage. However, the effects and …

The quest to understand the memory engram has intrigued humans for centuries. Recent
technological advances, including genetic labeling, imaging, optogenetic and chemogenetic …

Background In recent years, sleep problems have emerged as a significant factor in the
development of diseases that influence cognitive function. The inflammatory response may …

Sleep fragmentation (SF) is a common sleep problem experienced during the perioperative
period by older adults, and is associated with postoperative cognitive dysfunction (POCD) …

Recent studies in both humans and animal models call into question the completeness of
recovery after chronic sleep disruption. Studies in humans have identified cognitive domains …

Brain rhythms of sleep reflect neuronal activity underlying sleep‐associated memory
consolidation. The modulation of brain rhythms, such as the sleep slow oscillation (SO), is …

Microglia, resident immune cells in the central nervous system, constantly monitor the state
of the surrounding brain activity. The animal model induced by sleep deprivation (SD) is …