With the growing burden of cancer, parallel advancements in anticancer nanotechnological
solutions have been witnessed. Among the different types of cancers, breast cancer …

A drug's aqueous solubility is defined as the ability to dissolve in a particular solvent, and it
is currently a major hurdle in bringing new drug molecules to the market. According to some …

As a subclass of the biopharmaceutical classification system (BCS) class II, basic drugs
(BCS IIB) exhibit pH-dependent solubility and tend to generate supersaturation in the …

The rate and extent of drug dissolution and absorption from solid oral dosage forms is highly
dependent upon the volumes and distribution of gastric and small intestinal water. However …

This report describes the development of an orally active analgesic that resolves
inflammation and neuropathic pain without the addictive potential of opioids. EC5026 acts …

Apigenin (4′, 5, 7-trihydroxyflavone) is a plant flavone that has been found to have various
actions against cancer cells. We evaluated available evidence to determine whether it is …

The aim of this study was the development of griseofulvin (GRI) loaded β-cyclodextrin (β–
CD) based nanosponges for bitter taste masking, improving dissolution rate and oral …

Poorly water-soluble drugs are frequently encountered and present a most challengeable
difficulty in pharmaceutical development. Poor solubility of drugs can lead to suboptimal …

The objective of this study was to investigate the pH-dependent solubility and dissolution of
weakly basic Biopharmaceutical Classification Systems (BCS) class II drugs, characterized …

Abstract β-Cyclodextrin-based nanosponges (β-CDNSs) play an important role in new
arrays of agriculture, floriculture, cosmetics, medicine, high molecular weight proteins, novel …