Oxidative stress (OS), resulting from a disrupted balance between reactive oxygen species
(ROS) and protective antioxidants, is thought to play an important pathogenetic role in …

African swine fever virus (ASFV) infectious cycle starts with the viral adsorption and entry
into the host cell. Then, the virus is internalized via clathrin/dynamin mediated endocytosis …

Increased morbidity and mortality from coronavirus disease 2019 (COVID‐19) in people with
obesity have illuminated the intersection of obesity with impaired responses to infections …

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) dysregulates antiviral
signaling, immune response, and cell metabolism in human body. Viral genome and …

Cepharanthine (CEP) is a natural biscoclaurine alkaloid of plant origin and was recently
demonstrated to have anti‐severe acute respiratory syndrome coronavirus 2 (anti‐SARS …

The global spread of SARS-CoV-2 is posing major public health challenges. One unique
feature of SARS-CoV-2 spike protein is the insertion of multi-basic residues at the S1/S2 …

Viruses communicate with their hosts through interactions with proteins, lipids, and
carbohydrate moieties on the plasma membrane (PM), often resulting in viral absorption via …

Viruses have evolved to manipulate host lipid metabolism to benefit their replication cycle.
Enveloped viruses, including coronaviruses, use host lipids in various stages of the viral life …

NPC1 plays a central role in cholesterol egress from endolysosomes, a critical step for
maintaining intracellular cholesterol homeostasis. Despite recent advances in the field, the …

The unprecedent situation generated by the COVID-19 global emergency has prompted us
to actively work to fight against this pandemic by searching for repurposable agents among …