[HTML][HTML] Flavonoids and their anti-diabetic effects: Cellular mechanisms and effects to improve blood sugar levels

RK Al-Ishaq, M Abotaleb, P Kubatka, K Kajo… - Biomolecules, 2019 - mdpi.com
Diabetes mellitus (DM) is a prevailing global health metabolic disorder, with an alarming
incidence rate and a huge burden on health care providers. DM is characterized by the …

[HTML][HTML] Applications, phytochemistry, pharmacological effects, pharmacokinetics, toxicity of Scutellaria baicalensis Georgi. and its probably potential therapeutic …

JW Song, JY Long, L Xie, LL Zhang, QX Xie, HJ Chen… - Chinese Medicine, 2020 - Springer
Scutellaria baicalensis Georgi.(SB) is a common heat-clearing medicine in traditional
Chinese medicine (TCM). It has been used for thousands of years in China and its …

Promising influences of Scutellaria baicalensis and its two active constituents, baicalin, and baicalein, against metabolic syndrome: A review

V Baradaran Rahimi, VR Askari… - Phytotherapy …, 2021 - Wiley Online Library
Metabolic syndrome is known as a group of metabolic abnormalities with features including
central obesity, insulin resistance, hypercholesterolemia, hypertriglyceridemia, and …

[HTML][HTML] Carpachromene ameliorates insulin resistance in HepG2 cells via modulating IR/IRS1/PI3k/Akt/GSK3/FoxO1 pathway

R Alaaeldin, IAM Abdel-Rahman, HA Hassan… - Molecules, 2021 - mdpi.com
Insulin resistance contributes to several disorders including type 2 diabetes and
cardiovascular diseases. Carpachromene is a natural active compound that inhibits α …

Tetrahedral Framework Nucleic Acids Ameliorate Insulin Resistance in Type 2 Diabetes Mellitus via the PI3K/Akt Pathway

Y Li, Y Tang, S Shi, S Gao, Y Wang… - … Applied Materials & …, 2021 - ACS Publications
Insulin resistance (IR) is one of the essential conditions in the development of type 2
diabetes mellitus (T2DM). IR occurs in hepatic cells when the insulin receptor substrate-1 …

Molecular mechanism of the effect of Huanglian Jiedu decoction on type 2 diabetes mellitus based on network pharmacology and molecular docking

B Yin, YM Bi, GJ Fan, YQ Xia - Journal of Diabetes Research, 2020 - Wiley Online Library
Background. Huanglian Jiedu Decoction (HLJDD) is a Traditional Chinese Medicine (TCM)
formula comprising four herbal medicines. This decoction has long been used in China for …

Potential hypoglycemic, hypolipidemic, and anti-inflammatory bioactive components in Nelumbo nucifera leaves explored by bioaffinity ultrafiltration with multiple …

H Zhang, G Chen, Y Zhang, M Yang, J Chen, M Guo - Food Chemistry, 2022 - Elsevier
Abstract Leaf of Nelumbo nucifera Gaertn.(N. nucifera) has been widely used as the main
ingredient in lipid-lowering herbal teas and some prescriptions in China due to their …

Baicalin and its aglycone: a novel approach for treatment of metabolic disorders

P Fang, M Yu, M Shi, P Bo, X Gu, Z Zhang - Pharmacological Reports, 2020 - Springer
Background The current strategies for prevention and treatment of insulin resistance and
type 2 diabetes are not fully effective and frequently accompanied by many negative effects …

[HTML][HTML] A Systematic Review of Orthosiphon stamineus Benth. in the Treatment of Diabetes and Its Complications

Q Wang, J Wang, N Li, J Liu, J Zhou, P Zhuang… - Molecules, 2022 - mdpi.com
(1) Background: Orthosiphon stamineus Benth. is a traditional medicine used in the
treatment of diabetes and chronic renal failure in southern China, Malaysia, and Thailand …

Phenolic Constituents from Black Quinoa Alleviate Insulin Resistance in HepG2 Cells via Regulating IRS1/PI3K/Akt/GLUTs Signaling Pathways

M Cao, J Wang, X Jiang, Z Sun, L Zhao… - Journal of Agricultural …, 2023 - ACS Publications
Quinoa is a nutrient-rich pseudocereal with a lower glycemic index and glycemic load.
However, its therapeutic potency and underlying mechanism against insulin resistance (IR) …