Insight into the Substrate Specificity of Lactobacillus paracasei Aspartate Ammonia-Lyase

YH Huang, WC You, YJ Chen, JY Ciou, LS Hsieh - Fermentation, 2023 - mdpi.com
Aspartate ammonia-lyase (AAL) catalyzes the reversible conversion reactions of aspartate to
fumaric acid and ammonia. In this work, Lactobacillus paracasei LpAAL gene was …

Biotransformation of Dioscorea nipponica by Rat Intestinal Microflora and Cardioprotective Effects of Diosgenin

JF Feng, YN Tang, H Ji, ZG Xiao… - Oxidative medicine and …, 2017 - Wiley Online Library
Studying the biotransformation of natural products by intestinal microflora is an important
approach to understanding how and why some medicines—particularly natural medicines …

Delonix regia Leaf Extract (DRLE): A Potential Therapeutic Agent for Cardioprotection

LS Wang, CT Lee, WL Su, SC Huang, SC Wang - PloS one, 2016 - journals.plos.org
Delonix regia (Boj. Ex. Hook) is a flowering plant in the pea family found in tropical areas
and its leaves are used informally to treat diseases in folk medicine. However, the …

Storax, a promising botanical medicine for treating cardio-cerebrovascular diseases: a review

Z Xu, D Lu, J Yuan, M Ren, R Ma, Q Xie, Y Li… - Frontiers in …, 2021 - frontiersin.org
In recent years, the incidence and mortality of cardio-cerebrovascular diseases have been
increasing year by year, which has become global burden and challenge. Based on the …

Antioxidant serine-(NSAID) hybrids with anti-inflammatory and hypolipidemic potency

P Theodosis-Nobelos, G Papagiouvannis, P Tziona… - Molecules, 2021 - mdpi.com
A series of L-serine amides of antioxidant acids, such as Trolox,(E)-3-(3, 5-di-tert-butyl-4-
hydroxyphenyl) acrylic acid (phenolic derivative of cinnamic acid) and 3, 5-di-tert-butyl-4 …

Pharmacokinetic and permeation studies in rat brain of natural compounds led to investigate eugenol as direct activator of dopamine release in PC12 cells

B Pavan, A Bianchi, G Botti, L Ferraro… - International Journal of …, 2023 - mdpi.com
Eugenol, cinnamaldehyde and D-limonene, the main components of natural essential oils,
are endowed with antioxidant and anti-inflammatory properties which allow them to induce …

Sophora tonkinensis and active compounds inhibit mitochondrial impairments, inflammation, and LDLR deficiency in myocardial ischemia mice through regulating the …

SN Zhang, Q Liu, XZ Li, WD Yang, Y Zhou - Fitoterapia, 2024 - Elsevier
Ancient Chinese medicine literature and modern pharmacological studies show that
Sophora tonkinensis Gagnep.(ST) has a protective effect on the heart. A biolabel research …

Cinnamic aldehyde treatment alleviates chronic unexpected stress-induced depressive-like behaviors via targeting cyclooxygenase-2 in mid-aged rats

Y Yao, HY Huang, YX Yang, JY Guo - Journal of ethnopharmacology, 2015 - Elsevier
Ethnopharmacological relevance COX-2 has been considered as a potent molecular target
for prevention and therapy of depression. However, a recent study showed that COX-2 …

Cardioprotective effects of tannic acid on isoproterenol‐induced myocardial injury in rats: further insight into 'French Paradox'

X Hu, H Wang, X Lv, L Chu, Z Liu, X Wei… - Phytotherapy …, 2015 - Wiley Online Library
Tannic acid (TA) is a polyphenolic compound, which has shown diverse pharmacological
effects with antimutagenic, anticarcinogenic and antibactericidal properties. However …

The Guizhi Gancao decoction attenuates myocardial ischemia‐reperfusion injury by suppressing inflammation and cardiomyocyte apoptosis

Y Gao, G Song, YJ Cao, KP Yan, B Li… - Evidence‐Based …, 2019 - Wiley Online Library
Guizhi Gancao Decoction (GGD) is a well‐known traditional Chinese herbal medicine for the
treatment of various cardiovascular diseases, such as myocardial ischemia‐reperfusion (I/R) …