Placental malaria (PM) due to Plasmodium falciparum is a major cause of maternal, fetal
and infant mortality, but the mechanisms of pathogenesis and protective immunity are …

In areas where Plasmodium falciparum transmission is endemic, clinical immunity against
malaria is progressively acquired during childhood and adults are usually protected against …

Background Malaria in pregnancy has major impacts on mother and child health. To
complement existing interventions, such as intermittent preventive treatment and use of …

Plasmodium falciparum VAR2CSA binds to chondroitin sulfate A (CSA) on the surface of the
syncytiotrophoblast during placental malaria. This interaction facilitates placental …

The Plasmodium falciparum erythrocyte membrane protein 1 antigens that are inserted onto
the surface of P. falciparum infected erythrocytes play a key role both in the pathology of …

Placental malaria (PM) is a deadly syndrome most frequent and severe in first pregnancies.
PM results from accumulation of Plasmodium falciparum-infected erythrocytes (IE) that …

Plasmodium falciparum-infected erythrocytes (IE) sequester in the placenta via surface
protein VAR2CSA, which binds chondroitin sulfate A (CSA) expressed on the …

Plasmodium parasites are the causative agent of malaria, a disease that kills approximately
450,000 individuals annually, with the majority of deaths occurring in children under the age …

Pregnancy associated malaria (PAM) causes adverse pregnancy and birth outcomes owing
to Plasmodium falciparum accumulation in the placenta. Placental accumulation is mediated …

Background. Placental malaria is caused by Plasmodium falciparum–infected erythrocytes
(IEs) that surface-express VAR2CSA and bind chondroitin sulfate A. The inflammatory …