mRNA vaccines in disease prevention and treatment
G Zhang, T Tang, Y Chen, X Huang… - Signal Transduction and …, 2023 - nature.com
Abstract mRNA vaccines have emerged as highly effective strategies in the prophylaxis and
treatment of diseases, thanks largely although not totally to their extraordinary performance …
treatment of diseases, thanks largely although not totally to their extraordinary performance …
Tumor vaccination using messenger RNA: prospects of a future therapy
While the endeavor to vaccinate against cancer has been pursued for over 20 years, only
recently was the first tumor vaccine approved. Among the different antigen formats assessed …
recently was the first tumor vaccine approved. Among the different antigen formats assessed …
mRNA as a versatile tool for exogenous protein expression
AN Kuhn, T Beissert, P Simon, B Vallazza… - Current gene …, 2012 - ingentaconnect.com
Several viral and non-viral vectors have been developed for exogenous protein expression
in specific cells. Conventionally, this purpose is achieved through the use of recombinant …
in specific cells. Conventionally, this purpose is achieved through the use of recombinant …
mRNA cancer vaccines—messages that prevail
C Grunwitz, LM Kranz - Cancer Vaccines, 2017 - Springer
During the last decade, mRNA became increasingly recognized as a versatile tool for the
development of new innovative therapeutics. Especially for vaccine development, mRNA is …
development of new innovative therapeutics. Especially for vaccine development, mRNA is …
mRNA: a versatile molecule for cancer vaccines
Abstract mRNA vaccines are finally ready to assume their rightful place at the forefront of
nucleic acid-based vaccines. Major achievements within the last two decades have turned …
nucleic acid-based vaccines. Major achievements within the last two decades have turned …
Carcinoembryonic antigen (CEA)-based cancer vaccines: recent patents and antitumor effects from experimental models to clinical trials
M Turriziani, M Fantini, M Benvenuto… - Recent patents on …, 2012 - ingentaconnect.com
Carcinoembryonic antigen (CEA), a glycosylated protein of MW 180 kDa, is overexpressed
in a wide range of human carcinomas, including colorectal, gastric, pancreatic, non-small …
in a wide range of human carcinomas, including colorectal, gastric, pancreatic, non-small …
[HTML][HTML] RNA vaccines in cancer treatment
A Bringmann, SAE Held, A Heine… - BioMed Research …, 2010 - hindawi.com
The Cancer Report from the World Health Organization states that in the year 2000 12% of
all death cases worldwide were caused by cancer. In the western world, the cancer death …
all death cases worldwide were caused by cancer. In the western world, the cancer death …
The delivery of HBcAg via Tat-PTD enhances specific immune response and inhibits Hepatitis B virus replication in transgenic mice
X Chen, J Lai, Q Pan, Z Tang, Y Yu, G Zang - Vaccine, 2010 - Elsevier
Recent studies have indicated that the therapeutic vaccine based on enhancement of HBV-
specific cytotoxic T-lymphocyte (CTL) activity may lead to viral clearance in chronically …
specific cytotoxic T-lymphocyte (CTL) activity may lead to viral clearance in chronically …
Neem leaf glycoprotein enhances carcinoembryonic antigen presentation of dendritic cells to T and B cells for induction of anti-tumor immunity by allowing generation …
Vaccination with neem leaf glycoprotein matured carcinoembryonic antigen (CEA) pulsed
dendritic cells (DCs) enhances antigen-specific humoral and cellular immunity against CEA …
dendritic cells (DCs) enhances antigen-specific humoral and cellular immunity against CEA …