Apolipoprotein E (ApoE) is a multifunctional protein critical for lipid metabolism and
cholesterol homeostasis. In addition to being a well-known genetic determinant of both …

A growing body of evidence indicates that a neuropathological cross-talk takes place
between the coronavirus disease 2019 (COVID-19)-the pandemic severe pneumonia that …

APOE ε4 polymorphism has been recently described as a possible association with
cognitive deficits in COVID-19 patients. This research aimed to establish the correlation …

ACE2's impact on the severity of COVID-19 is widely discussed but still controversial. To
estimate its role in aspects of the main risk factors and comorbidities, we involved post …

The role of genetics as a predisposing factor related to an increased risk of developing long
COVID symptomatology is under debate. The aim of the current secondary analysis was to …

Coronavirus disease 2019 (COVID-19) was initially considered a primarily respiratory
disease but is now known to affect other organs including the heart and brain. A major route …

Patients with Alzheimer's disease (AD) inheriting Apolipoprotein (APOE) ε4 are susceptible
to COVID-19, but the underlying mechanism of how such a neurodegenerative disease …

ABSTRACT A dysfunction of human host genes and proteins in coronavirus infectious
disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 …

Background Alzheimer's disease (AD) is a progressive neurodegenerative disease and
apolipoprotein E (APOE) genotypes (APOE2, APOE3, and APOE4) show different AD …

Apolipoprotein E (apoE) is a 299 amino acid protein with vital functions in transporting
plasma cholesterol from peripheral tissues to the liver to be metabolized (1). The human …