Novel cardiovascular protective effects of RhoA signaling and its therapeutic implications

JEC Soh, A Shimizu, A Sato, H Ogita - Biochemical Pharmacology, 2023 - Elsevier
Ras homolog gene family member A (RhoA) belongs to the Rho GTPase superfamily, which
was first studied in cancers as one of the essential regulators controlling cellular function …

Proteomic Analysis of Human Macrophages Overexpressing Angiotensin-Converting Enzyme

D Oosthuizen, TA Ganief, KE Bernstein… - International Journal of …, 2024 - mdpi.com
Angiotensin converting enzyme (ACE) exerts strong modulation of myeloid cell function
independently of its cardiovascular arm. The success of the ACE-overexpressing murine …

Pinocembrin attenuates susceptibility to atrial fibrillation in rats with pulmonary arterial hypertension

Y Yi, Y Tianxin, L Zhangchi, Z Cui, W Weiguo… - European Journal of …, 2023 - Elsevier
Background Pulmonary arterial hypertension (PAH) is a disease characterized by
pulmonary vascular remodeling that triggers fibrosis and excessive myocardium apoptosis …