Postoperative delirium and cognitive dysfunction (POCD) are topics of special importance in
the geriatric surgical population. They are separate entities, whose relationship has yet to be …

Older individuals often experience declines in cognitive function after events (eg infection, or
injury) that trigger activation of the immune system. This occurs at least in part because …

Objective: Although postoperative cognitive dysfunction (POCD) often complicates recovery
from major surgery, the pathogenic mechanisms remain unknown. We explored whether …

Background Early identification of patients at risk for delirium is important, since adequate
well timed interventions could prevent occurrence of delirium and related detrimental …

Subthalamic nucleus (STN) deep brain stimulation (DBS) is currently the most common
therapeutic surgical procedure for patients with Parkinson's disease (PD) who have failed …

Post-operative cognitive complications such as delirium have been consistently associated
with poor short and long term outcomes, and the role of anesthesia, particularly the role of …

Background Postoperative cognitive dysfunction is being increasingly reported as a
complication. The authors investigated the role of cytokine-mediated inflammation within the …

IMPLICATIONS: The current systematic review demonstrates that there are only a few
clinical trials that compare opioid analgesics or analgesic modalities. Meperidine appears to …

We report that a peripheral injection of Escherichia coli produces both anterograde and
retrograde amnesia in 24 month old, but not 3 month old rats for memories that depend on …

Prolonged postoperative cognitive dysfunction (POCD) is reported to occur frequently after
cardiac surgery. However, it is rarely assessed in routine clinical practice and receives little …