[HTML][HTML] Non-canonical WNT signalling in cardiovascular disease: mechanisms and therapeutic implications
I Akoumianakis, M Polkinghorne… - Nature Reviews …, 2022 - nature.com
WNT signalling comprises a diverse spectrum of receptor-mediated pathways activated by a
large family of WNT ligands and influencing fundamental biological processes. WNT …
large family of WNT ligands and influencing fundamental biological processes. WNT …
[HTML][HTML] WNT signaling in disease
Developmental signaling pathways control a vast array of biological processes during
embryogenesis and in adult life. The WNT pathway was discovered simultaneously in …
embryogenesis and in adult life. The WNT pathway was discovered simultaneously in …
WNT signaling in cardiac and vascular disease
S Foulquier, EP Daskalopoulos, G Lluri… - Pharmacological …, 2018 - ASPET
WNT signaling is an elaborate and complex collection of signal transduction pathways
mediated by multiple signaling molecules. WNT signaling is critically important for …
mediated by multiple signaling molecules. WNT signaling is critically important for …
[HTML][HTML] Wnt signaling in intestinal inflammation
L Moparthi, S Koch - Differentiation, 2019 - Elsevier
Chronic inflammatory bowel diseases, including Crohn's disease and ulcerative colitis, are a
major health burden worldwide. Numerous conserved signaling pathways control tissue …
major health burden worldwide. Numerous conserved signaling pathways control tissue …
Yap promotes noncanonical Wnt signals from cardiomyocytes for heart regeneration
Rationale: During neonatal heart regeneration, the fibrotic response, which is required to
prevent cardiac rupture, resolves via poorly understood mechanisms. Deletion of the Hippo …
prevent cardiac rupture, resolves via poorly understood mechanisms. Deletion of the Hippo …
[HTML][HTML] 3D-printed dermis-specific extracellular matrix mitigates scar contraction via inducing early angiogenesis and macrophage M2 polarization
L Chen, Z Li, Y Zheng, F Zhou, J Zhao, Q Zhai… - Bioactive materials, 2022 - Elsevier
Scar contraction frequently happens in patients with deep burn injuries. Hitherto, porcine
dermal extracellular matrix (dECM) has supplied microenvironments that assist in wound …
dermal extracellular matrix (dECM) has supplied microenvironments that assist in wound …
Wnt5a and Wnt11 as acute respiratory distress syndrome biomarkers for severe acute respiratory syndrome coronavirus 2 patients
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection has spread globally, resulting in declaration of …
coronavirus 2 (SARS-CoV-2) infection has spread globally, resulting in declaration of …
[HTML][HTML] Cardiac Wnt5a and Wnt11 promote fibrosis by the crosstalk of FZD5 and EGFR signaling under pressure overload
Y Zou, L Pan, Y Shen, X Wang, C Huang, H Wang… - Cell death & …, 2021 - nature.com
Progressive cardiac fibrosis accelerates the development of heart failure. Here, we aimed to
explore serum Wnt5a and Wnt11 levels in hypertension patients, the roles of Wnt5a and …
explore serum Wnt5a and Wnt11 levels in hypertension patients, the roles of Wnt5a and …
[HTML][HTML] The role of Wnt signaling in the healing myocardium: a focus on cell specificity
IS Meyer, F Leuschner - Basic Research in Cardiology, 2018 - Springer
Various cell types are involved in the healing process after myocardial infarction (MI).
Besides cardiac resident cells (such as cardiomyocytes, fibroblasts and endothelial cells) …
Besides cardiac resident cells (such as cardiomyocytes, fibroblasts and endothelial cells) …
Wnt signaling in cardiac disease
KCM Hermansand… - Comprehensive …, 2015 - cris.maastrichtuniversity.nl
Wnt signaling encompasses multiple and complex signaling cascades and is involved in
many developmental processes such as tissue patterning, cell fate specification, and control …
many developmental processes such as tissue patterning, cell fate specification, and control …