Prevention of cardiovascular disease (CVD) remains one of the largest public health
challenges of our time. Identifying individuals at increased cardiovascular risk at an …

CKD frequently leads to chronic cardiac dysfunction. This complex relationship has been
termed as cardiorenal syndrome type 4 or cardio-renal link. Despite numerous studies and …

Cardiovascular (CV) disease remains an important cause of morbidity and mortality for
patients with chronic kidney disease (CKD). Although clustering of traditional risk factors with …

BACKGROUND: Here, we assessed the role of cellular senescence and the senescence
associated secretory phenotype (SASP) in age-related aortic stiffening and endothelial …

The kidney-heart relationship has raised interest for the medical population since its vast
and complex interaction significantly impacts health. Chronic kidney disease (CKD) …

First, we would like to briefly describe the changes in the arterial medial layer that occur in
association with atherosclerotic vascular damage, affecting the arterial stiffness5-8). The …

Hypertension (HTN) is an important risk factor for cardiovascular disease (CVD) but the
association between HTN and CVD cannot be explained by average blood pressure (BP) …

Advanced glycation end products (AGEs) are aging products. In chronic kidney disease
(CKD), AGEs accumulate due to the increased production, reduced excretion, and the …

Chronic kidney disease (CKD) is a major public health concern. Despite many potentially life-
threatening conditions that can accompany kidney disease, cardiovascular disease (CVD) …

Patients with chronic kidney disease (CKD) are at increased risk of cardiovascular disease.
This increased risk cannot be fully explained by traditional risk factors such as hypertension …