Cisplatin and other platinum-based drugs, such as carboplatin, ormaplatin, and oxaliplatin,
have been widely used to treat a multitude of human cancers. However, a considerable …

Cisplatin is a widely used chemotherapeutic agent used to treat solid tumours, such as
ovarian, head and neck, and testicular germ cell. A known complication of cisplatin …

Background Flavonoids are reported to modulate the composition of gut microbiota, which
play an important role in preventing obesity and associated metabolic diseases. In this …

As a kind of environmental pollutant, heavy metal Cadmium (Cd) exists widely in the
environment. It is well known that Cd can accumulate and cause damage in liver, kidney and …

Abstract 3, 3′, 4, 4′, 5-pentachlorobiphenyl (PCB126) is extensively utilized in electronic
products, lubricant, and insecticide due to its excellent chemical stability and insulation …

The contamination of deoxynivalenol (DON) in feed is a global problem, which seriously
threatens the productivity efficiency and welfare of farm animals and the food security of …

Significance: Nuclear factor erythroid 2 (NFE2)-related factor 2 (NFE2L2, or NRF2) is a
transcription factor predominantly affecting the expression of antioxidant genes. NRF2 plays …

Background Many flavonoids have various beneficial actions like anti-inflammatory, anti-
carcinogenic properties and many other clinical conditions. Astilbin is one such flavanoid …

Objective The basic pathological changes of primary ovarian insufficiency (POI) include
ovarian tissue fibrosis and follicular development disorders. The human umbilical cord …

Chlorogenic acid (CA), the ester of caffeic acid and quinic acid, is one of the most abundant
polyphenols in coffee, and has multiple pharmacological functions. The present study is …