Recent advances in understanding enteric pathogenic Escherichia coli

MA Croxen, RJ Law, R Scholz… - Clinical microbiology …, 2013 - Am Soc Microbiol
Although Escherichia coli can be an innocuous resident of the gastrointestinal tract, it also
has the pathogenic capacity to cause significant diarrheal and extraintestinal diseases …

Metabolites of microbiota response to tryptophan and intestinal mucosal immunity: A therapeutic target to control intestinal inflammation

J Zhang, S Zhu, N Ma, LJ Johnston… - Medicinal Research …, 2021 - Wiley Online Library
In a complex, diverse intestinal environment, commensal microbiota metabolizes excessive
dietary tryptophan to produce more bioactive metabolites connecting with kinds of diverse …

Identification of mucin degraders of the human gut microbiota

S Raimondi, E Musmeci, F Candeliere, A Amaretti… - Scientific reports, 2021 - nature.com
Mucins are large glycoproteins consisting of approximately 80% of hetero-oligosaccharides.
Gut mucin degraders of healthy subjects were investigated, through a culture dependent …

Targeting the gut-liver-immune axis to treat cirrhosis

TH Tranah, LA Edwards, B Schnabl, DL Shawcross - Gut, 2021 - gut.bmj.com
Cirrhotic portal hypertension is characterised by development of the decompensating events
of ascites, encephalopathy, portal hypertensive bleeding and hepatorenal syndrome, which …

[HTML][HTML] Adherence patterns of Escherichia coli in the intestine and its role in pathogenesis

DK Govindarajan, N Viswalingam, Y Meganathan… - Medicine in …, 2020 - Elsevier
Gut microbiota plays an important role in maintaining a healthy intestine. Escherichia coli (E.
coli) is a commensal bacteria colonizes the mucous membranes of the gut, intestine, and …

Microbial adaptation to the healthy and inflamed gut environments

Y Guo, S Kitamoto, N Kamada - Gut Microbes, 2020 - Taylor & Francis
There are 100 trillion diverse bacterial residents in the mammalian gut. Commensal
bacterial species/strains cooperate and compete with each other to establish a well …

Spatial analysis of gut microbiome reveals a distinct ecological niche associated with the mucus layer

K Duncan, K Carey-Ewend, S Vaishnava - Gut Microbes, 2021 - Taylor & Francis
Mucus-associated bacterial communities are critical for determining disease pathology and
promoting colonization resistance. Yet the key ecological properties of mucus resident …

[HTML][HTML] Faecal cytokine profiling as a marker of intestinal inflammation in acutely decompensated cirrhosis

A Riva, EH Gray, S Azarian, A Zamalloa, MJW McPhail… - JHEP reports, 2020 - Elsevier
Background & Aims Gut dysbiosis and inflammation perpetuate loss of gut barrier integrity
(GBI) and pathological bacterial translocation (BT) in cirrhosis, contributing to infection risk …

Identification and characterisation of enteroaggregative Escherichia coli subtypes associated with human disease

SJ Ellis, LC Crossman, CJ McGrath, MA Chattaway… - Scientific Reports, 2020 - nature.com
Enteroaggregative E. coli (EAEC) are a major cause of diarrhoea worldwide. Due to their
heterogeneity and carriage in healthy individuals, identification of diagnostic virulence …

Pathogenesis of human enterovirulent bacteria: lessons from cultured, fully differentiated human colon cancer cell lines

V Liévin-Le Moal, AL Servin - Microbiology and Molecular Biology …, 2013 - Am Soc Microbiol
Hosts are protected from attack by potentially harmful enteric microorganisms, viruses, and
parasites by the polarized fully differentiated epithelial cells that make up the epithelium …