Berberine and barberry (Berberis vulgaris): A clinical review

M Imenshahidi, H Hosseinzadeh - Phytotherapy Research, 2019 - Wiley Online Library
Barberry (Berberis vulgaris L.) has different medicinal applications in folk medicine of Iran.
Berberine, an alkaloid constituent of this plant, is present in the roots, rhizomes, stem, and …

Management of statin intolerance in 2018: still more questions than answers

PP Toth, AM Patti, RV Giglio, D Nikolic… - American Journal of …, 2018 - Springer
Statin therapy is generally well tolerated and very effective in the prevention and treatment of
cardiovascular disease, regardless of cholesterol levels; however, it can be associated with …

[HTML][HTML] Phytopharmacology and clinical updates of Berberis species against diabetes and other metabolic diseases

T Belwal, A Bisht, HP Devkota, H Ullah… - Frontiers in …, 2020 - frontiersin.org
The incidences of diabetic mellitus and other metabolic diseases such as hypertension and
hyperlipidemia are increasing worldwide; however, the current treatment is not able to …

Regulation of PCSK9 by nutraceuticals

AA Momtazi, M Banach, M Pirro, N Katsiki… - Pharmacological …, 2017 - Elsevier
PCSK9 (proprotein convertase subtilisin kexin type 9) is a liver secretory enzyme that
regulates plasma low-density lipoprotein (LDL) cholesterol (LDL-C) levels through …

The effects of a nutraceutical combination on plasma lipids and glucose: a systematic review and meta-analysis of randomized controlled trials

M Pirro, MR Mannarino, V Bianconi… - Pharmacological …, 2016 - Elsevier
Dyslipidemia and hyperglycemia are associated with an increased risk of ischemic
cardiovascular disease. Positive effects of a nutraceutical combination comprising red yeast …

Functional food red yeast rice (RYR) for metabolic syndrome amelioration: a review on pros and cons

S Patel - World journal of microbiology and biotechnology, 2016 - Springer
Red yeast rice (RYR), the fermentation product of mold Monascus purpureus has been an
integral part of Oriental food and traditional Chinese medicine, long before the discovery of …

Berberine: new insights from pharmacological aspects to clinical evidences in the management of metabolic disorders

C Caliceti, P Franco, S Spinozzi, A Roda… - Current Medicinal …, 2016 - ingentaconnect.com
Berberine is a quaternary ammonium salt from the protoberberine group of isoquinoline
alkaloids found in such plants as gender Berberis. Berberine is recognised to improve …

[HTML][HTML] A nutraceutical approach (Armolipid Plus) to reduce total and LDL cholesterol in individuals with mild to moderate dyslipidemia: review of the clinical evidence

V Barrios, C Escobar, AFG Cicero, D Burke… - Atherosclerosis …, 2017 - Elsevier
Compelling evidence supports the effectiveness of the reduction of total and LDL cholesterol
(TC and LDL-C) in primarily preventing cardiovascular events, within the framework of life …

Update on the benefits and mechanisms of action of the bioactive vegetal alkaloid berberine on lipid metabolism and homeostasis

Y Wang, JA Zidichouski - Cholesterol, 2018 - Wiley Online Library
Elevation of circulating levels of blood cholesterol, especially LDL cholesterol, and/or the
decrease of HDL cholesterol levels have long been recognized as primary risk factors for …

Combinations of phytomedicines with different lipid lowering activity for dyslipidemia management: the available clinical data

AFG Cicero, A Colletti - Phytomedicine, 2016 - Elsevier
Background Cardiovascular diseases are the primary cause of death and the leading cause
of disability in industrialized countries. Dyslipidemia is a major independent and reversible …