An ancient conflict between hosts and pathogens has driven the innate and adaptive arms of
immunity. Knowledge about this interplay can not only help us identify biological …

Severe cases of SARS-CoV-2 infection are characterized by an immune response that leads
to the overproduction of pro-inflammatory cytokines, resulting in lung damage …

Knockout of the ORF8 protein has repeatedly spread through the global viral population
during SARS-CoV-2 evolution. Here we use both regional and global pathogen sequencing …

SARS-CoV-2 has caused an estimated 7 million deaths worldwide to date. A secreted SARS-
CoV-2 accessory protein, known as open reading frame 8 (ORF8), elicits inflammatory …

Severe acute respiratory syndrome coronavirus 2 XBB. 1.5 is the first recombinant lineage to
predominate at the country and global scales. Very interestingly, like the Marseille‐4B …

Objective This study aims to analyze the molecular characteristics of the novel coronavirus
(SARS-CoV-2) Omicron variant BA. 2.76 in Jining City, China. Methods Whole-genome …

SARS-CoV-2 is a highly pathogenic respiratory virus that successfully initiates and
establishes its infection at the respiratory mucosa. However, little is known about how SARS …

The studies reported here focus on the impact of pre-existing CD4 T cell immunity on the first
encounter with SARS-CoV-2. They leverage PBMC samples from plasma donors collected …

Introduction: Open Reading Frame 8 (ORF8) is a 121 amino acid length SARS-CoV-2
specific accessory protein that plays crucial roles in viral infectivity, and pathogenesis …

The genome of severe acute respiratory coronavirus-2 (SARS-CoV-2), the virus responsible
for coronavirus disease 2019 (COVID-19), has undergone a rapid evolution, resulting in the …