A diverse array of biologically active, lipid-soluble alkaloids have been discovered in
amphibian skin. Such alkaloids include the following: the steroidal samandarines from …

Amphibians occupy a wide range of habitat types from arid deserts to deep freshwater lakes;
they may spend most of their life underground or high in cloud forest canopy. Some are …

Despite the impressive growth of knowledge on the phylogenetic systematics of dart-poison
frogs and their relatives (Dendrobatoidea) over the past decade, many problems remain to …

Through gradual acquisition of a set of adaptations, both morphofunctional and behavioural,
the first amphibians were able to spend longer periods in a terrestrial environment. The …

Cutaneous granular glands are a shared character of adult amphibians, including
caecilians, and are thought to be the source of most biologically active compounds in …

The “geographic mosaic” approach to understanding coevolution is predicated on the
existence of variable selection across the landscape of an interaction between species. A …

There is an intuitive appeal to viewing natural struggles among species as arms races
between enemies. Consider the sitand-wait predator in his shiny patrol car who sits behind …

Poisons are common in nature, where they often serve the organism in chemical defense.
Such poisons either are produced de novo or are sequestered from dietary sources or …

Amphibian skin has provided a wide range of biologically active alkaloids. During the past
30 years, over 400 alkaloids of over 20 structural classes have been detected. These …

Ethnopharmacological relevance Among amphibians, 15 of the 47 species reported to be
used in traditional medicines belong to the family Bufonidae, which demonstrates their …