[HTML][HTML] Nano toolbox in immune modulation and nanovaccines

M Azharuddin, GH Zhu, A Sengupta, J Hinkula… - Trends in …, 2022 - cell.com
Despite the great success of vaccines over two centuries, the conventional strategy is based
on attenuated/altered microorganisms. However, this is not effective for all microbes and …

PLGA particles in immunotherapy

D Horvath, M Basler - Pharmaceutics, 2023 - mdpi.com
Poly (lactic-co-glycolic acid)(PLGA) particles are a widely used and extensively studied drug
delivery system. The favorable properties of PLGA such as good bioavailability, controlled …

PLGA-based micro/nanoparticles: an overview of their applications in respiratory diseases

X Guo, X Zuo, Z Zhou, Y Gu, H Zheng, X Wang… - International Journal of …, 2023 - mdpi.com
Respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD),
are critical areas of medical research, as millions of people are affected worldwide. In fact …

Eupatilin suppresses OVA-induced asthma by inhibiting NF-κB and MAPK and activating Nrf2 signaling pathways in mice

D Bai, T Sun, F Lu, Y Shen, Y Zhang, B Zhang… - International Journal of …, 2022 - mdpi.com
To investigate the effect of eupatilin in asthma treatment, we evaluated its therapeutic effect
and related signal transduction in OVA-induced asthmatic mice and LPS-stimulated …

Recent advances in nanomaterials for asthma treatment

X Zuo, X Guo, Y Gu, H Zheng, Z Zhou, X Wang… - International Journal of …, 2022 - mdpi.com
Asthma is a chronic airway inflammatory disease with complex mechanisms, and these
patients often encounter difficulties in their treatment course due to the heterogeneity of the …

Current research into A20 mediation of allergic respiratory diseases and its potential usefulness as a therapeutic target

Y Liu, K Xu, Y Yao, Z Liu - Frontiers in Immunology, 2023 - frontiersin.org
Allergic airway diseases are characterized by excessive and prolonged type 2 immune
responses to inhaled allergens. Nuclear factor κB (NF-κB) is a master regulator of the …

Targeting eosinophils in chronic respiratory diseases using nanotechnology-based drug delivery

P Sharma, DS Dhanjal, C Chopra… - Chemico-Biological …, 2022 - Elsevier
Abstract Asthma, COPD, COVID-19, EGPA, Lung cancer, and Pneumonia are major chronic
respiratory diseases (or CRDs) affecting millions worldwide and account for substantial …

Bridging micro/nano-platform and airway allergy intervention

MJ Sun, Z Teng, PS Fan, XG Chen, Y Liu - Journal of Controlled Release, 2022 - Elsevier
Allergic airway diseases, with incidence augmenting visibly as industrial development and
environmental degradation, are characterized by sneezing, itching, wheezing, chest …

Nanotechnology-based therapeutics for targeting inflammatory lung diseases

CY Loo, WH Lee - Nanomedicine, 2022 - Taylor & Francis
The physiochemical properties of drugs used in treating inflammation-associated lung
diseases (ie, asthma, chronic obstructive pulmonary disease, pulmonary fibrosis) play an …

Solid lipid nanoparticle delivery of rhynchophylline enhanced the efficiency of allergic asthma treatment via the upregulation of suppressor of cytokine signaling 1 by …

C Lv, H Li, H Cui, Q Bi, M Wang - Bioengineered, 2021 - Taylor & Francis
Allergic asthma is one of the most common chronic airway diseases, and there is still a lack
of effective drugs for the treatment of allergic asthma. The purpose of this work is to formulate …