Most free-living organisms require the synthesis and/or acquisition of purines and
pyrimidines, which form the basis of nucleotides, to survive. In most bacteria, the nucleotides …

Quorum sensing (QS) is a widespread phenomenon in the microbial world that has
important implications in the coordination of population-wide responses in several bacterial …

Staphylococcus aureus is a leading cause of both community-and hospital-acquired
infections that are increasingly antibiotic resistant. The emergence of S. aureus resistance to …

Abstract Streptococcus pyogenes (Group A Streptococcus, GAS) remains a major public
health burden worldwide, infecting over 750 million people leading to over 500,000 deaths …

In recent decades, fungal infections have emerged as an important health problem
associated with more people who present deficiencies in the immune system, such as HIV or …

Bloodstream infection is a major public health concern associated with high mortality and
high healthcare costs worldwide. Bacteremia can trigger fatal sepsis whose prevention …

Copper (Cu) is an essential metal for bacterial physiology but in excess it is bacteriotoxic. To
limit Cu levels in the cytoplasm, most bacteria possess a transcriptionally responsive system …

The evolution of resistance in Salmonella to fluoroquinolones (FQs) under a broad range of
sub-inhibitory concentrations (sub-MICs) has not been systematically studied. This study …

The critical role of the intestinal microbiota in human health and disease is well recognized.
Nevertheless, there are still large gaps in our understanding of the functions and …

Streptococcus pyogenes, also known as group A Streptococcus (GAS), is an exclusively
human Gram-positive bacterial pathogen ranked among the 'top 10'causes of infection …