Origin of spliceosomal introns and alternative splicing

M Irimia, SW Roy - Cold Spring Harbor perspectives in …, 2014 - cshperspectives.cshlp.org
In this work we review the current knowledge on the prehistory, origins, and evolution of
spliceosomal introns. First, we briefly outline the major features of the different types of …

Impact of gene gains, losses and duplication modes on the origin and diversification of vertebrates

C Cañestro, R Albalat, M Irimia… - Seminars in cell & …, 2013 - Elsevier
The study of the evolutionary origin of vertebrates has been linked to the study of genome
duplications since Susumo Ohno suggested that the successful diversification of vertebrate …

Extensive conservation of ancient microsynteny across metazoans due to cis-regulatory constraints

M Irimia, JJ Tena, MS Alexis… - Genome …, 2012 - genome.cshlp.org
The order of genes in eukaryotic genomes has generally been assumed to be neutral, since
gene order is largely scrambled over evolutionary time. Only a handful of exceptional …

FREEDA: An automated computational pipeline guides experimental testing of protein innovation

D Dudka, RB Akins, MA Lampson - Journal of Cell Biology, 2023 - rupress.org
Cell biologists typically focus on conserved regions of a protein, overlooking innovations that
can shape its function over evolutionary time. Computational analyses can reveal potential …

Quantification provides a conceptual basis for convergent evolution

MP Speed, K Arbuckle - Biological Reviews, 2017 - Wiley Online Library
While much of evolutionary biology attempts to explain the processes of diversification, there
is an important place for the study of phenotypic similarity across life forms. When similar …

Genealogical correspondence of a forebrain centre implies an executive brain in the protostome–deuterostome bilaterian ancestor

GH Wolff, NJ Strausfeld - Philosophical Transactions of …, 2016 - royalsocietypublishing.org
Orthologous genes involved in the formation of proteins associated with memory acquisition
are similarly expressed in forebrain centres that exhibit similar cognitive properties. These …

Unique evolutionary trajectories in repeated adaptation to hydrogen sulphide‐toxic habitats of a neotropical fish (Poecilia mexicana)

M Pfenninger, S Patel, L Arias‐Rodriguez… - Molecular …, 2015 - Wiley Online Library
Replicated ecological gradients are prime systems to study processes of molecular
evolution underlying ecological divergence. Here, we investigated the repeated adaptation …

Evolution of protein indels in plants, animals and fungi

P Ajawatanawong, SL Baldauf - BMC evolutionary biology, 2013 - Springer
Background Insertions/deletions (indels) in protein sequences are useful as drug targets,
protein structure predictors, species diagnostics and evolutionary markers. However there is …

Helical antifreeze proteins have independently evolved in fishes on four occasions

LA Graham, RS Hobbs, GL Fletcher, PL Davies - PLoS One, 2013 - journals.plos.org
Alanine-rich α-helical (type I) antifreeze proteins (AFPs) are produced by a variety of fish
species from three different orders to protect against freezing in icy seawater. Interspersed …

Recurrent speciation of a tomato yellow leaf curl geminivirus in Portugal by recombination

E Fiallo-Olivé, HP Trenado, D Louro… - Scientific reports, 2019 - nature.com
Recurrent evolution can involve interspecific interactions, recognized to play a primary role
in the diversification and organization of life. Both in the plant and animal kingdoms, the …