The effects of intranasal dexmedetomidine premedication in children: a systematic review and meta-analysis
JH Jun, KN Kim, JY Kim… - Canadian Journal of …, 2017 - search.proquest.com
The effects of intranasal dexmedetomidine premedication in children: a systematic review
and meta-analysis Page 1 REVIEW ARTICLE/BRIEF REVIEW The effects of intranasal …
and meta-analysis Page 1 REVIEW ARTICLE/BRIEF REVIEW The effects of intranasal …
Benzodiazepine metabolism: an analytical perspective
R Mandrioli, L Mercolini, MA Raggi - Current drug metabolism, 2008 - ingentaconnect.com
Benzodiazepines are currently among the most frequently prescribed drugs all over the
world. They act as anxiolytics, sedatives, hypnotics, amnesics, antiepileptics and muscle …
world. They act as anxiolytics, sedatives, hypnotics, amnesics, antiepileptics and muscle …
Prediction of the clearance of eleven drugs and associated variability in neonates, infants and children
TN Johnson, A Rostami-Hodjegan, GT Tucker - Clinical pharmacokinetics, 2006 - Springer
Background Prediction of the exposure of neonates, infants and children to xenobiotics is
likely to be more successful using physiologically based pharmacokinetic models than …
likely to be more successful using physiologically based pharmacokinetic models than …
Regulatory experience with physiologically based pharmacokinetic modeling for pediatric drug trials
R Leong, MLT Vieira, P Zhao… - Clinical …, 2012 - Wiley Online Library
Physiologically based pharmacokinetic (PBPK) approaches that incorporate the
developmental physiology and ontogeny of cytochrome P450 (CYP) enzymes may have …
developmental physiology and ontogeny of cytochrome P450 (CYP) enzymes may have …
Prediction of drug disposition in infants and children by means of physiologically based pharmacokinetic (PBPK) modelling: theophylline and midazolam as model …
S Björkman - British journal of clinical pharmacology, 2005 - Wiley Online Library
Aims To create a general physiologically based pharmacokinetic (PBPK) model for drug
disposition in infants and children, covering the age range from birth to adulthood, and to …
disposition in infants and children, covering the age range from birth to adulthood, and to …
A mechanistic approach for the scaling of clearance in children
Background and objective Clearance is an important pharmacokinetic concept for scaling
dosage, understanding the risks of drug-drug interactions and environmental risk …
dosage, understanding the risks of drug-drug interactions and environmental risk …
Scaling clearance in paediatric pharmacokinetics: all models are wrong, which are useful?
E Germovsek, CIS Barker, M Sharland… - British journal of …, 2017 - Wiley Online Library
Linked Articles This article is commented on in the editorial by Holford NHG and Anderson
BJ. Why standards are useful for predicting doses. Br J Clin Pharmacol 2017; 83: 685–7. doi …
BJ. Why standards are useful for predicting doses. Br J Clin Pharmacol 2017; 83: 685–7. doi …
Alginate-based drug oral targeting using bio-micro/nano encapsulation technologies
SR Wagle, B Kovacevic, D Walker… - Expert Opinion on …, 2020 - Taylor & Francis
Introduction Oral delivery is the most common administrated drug delivery path. However,
oral administration of lipophilic drugs has some limitations: they have poor dose-response …
oral administration of lipophilic drugs has some limitations: they have poor dose-response …
[HTML][HTML] Premedication with dexmedetomidine in pediatric patients: a systematic review and meta-analysis
K Peng, S Wu, F Ji, J Li - Clinics, 2014 - SciELO Brasil
Premedication is important in pediatric anesthesia. This meta-analysis aimed to investigate
the role of dexmedetomidine as a premedicant for pediatric patients. A systematic literature …
the role of dexmedetomidine as a premedicant for pediatric patients. A systematic literature …
Premedication with clonidine is superior to benzodiazepines. A meta analysis of published studies
Background: Premedication is considered important in pediatric anesthesia.
Benzodiazepines are the most commonly used premedication agents. Clonidine, an α2 …
Benzodiazepines are the most commonly used premedication agents. Clonidine, an α2 …